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  • NOW FOODS SAMe 100mg 30 tab.
  • NOW FOODS SAMe 100mg 30 tab.
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Since 2005  sales@mz-store.co.uk  7767803657
SAMe 100mg SAMe 100mg

Now Foods SAMe is the best absorbed form of S-adenosylmethionine on the market which produces far-reaching effects on many systems, improves significantly memory and focus, stabilises mood, helps combat depression and osteoarthritis, promotes a peaceful sleep and prevents inflammation.

S-adenosylmethionine is a natural substance that is a source of methyl groups. Binding and cleavage of these groups are one of the mechanisms which regulate metabolism, including the expression of specific genes. SAMe is reported to have a central effect by stabilising mood and the peripheral one by regulating bone metabolism and the endocrine system.

S-adenosylmethionine in this supplement is one of the best absorbed forms on the market. After entering the bloodstream, it is distributed in the serum in a free form (not bound to proteins) and transported to cells with the aid of SAMC.

Methionine metabolism

S-adenosylmethionine is formed by combining methionine, an indispensable amino acid found in the body only when provided from external sources (food), and ATP, a molecule synthesised during energy metabolism. Subsequently, numerous cyclic metabolic processes lead to the formation of such metabolites as S-adenosylhomocysteine or homocysteine till the end of the cycle.

High homocysteine levels have a potential atherogenic effect – it may speed up the progression of atherosclerosis. In order to prevent the formation of this compound, it is important to supplement with B vitamins – B12, folic acid and also B6, whose presence help end the cycle of methionine metabolism.

Furthermore, it has been demonstrated that SAMe supplementation does not lead to the accumulation of homocysteine and thus development of atherosclerotic plaque.

Antidepressant properties

Studies have shown that individuals with diagnosed depression suffer from SAMe deficiency in the central nervous system. This is probably caused by two mechanisms. The first one is folic acid deficiency, which was observed in a major group of study participants. The second one arises from the malfunctioning of the enzyme catalysing a reaction in which ATP is bound to methionine.

The administration of SAMe brought suprising results in comparison with tricyclic antidepressants. It has been therefore suggested that SAMe may relieve symptoms of depression.

In addition, S-adenosylmethionine is a donor of methyl groups in the synthesis of various neurotransmitters – acetylcholine, noradrenaline, dopamine and melatonin – which have an impact on cognitive functions of the body and help also modulate mood and regulate the sleep-wake rhythm.

Osteoarticular health

Persons who train hard or elderly individuals suffer often from osteoarthitis. This disease is inflammatory and leads to slow degeneration of joint cartilages, accompanied by pain and impaired mobility. Non-steroidal anti-inflammatory medicines are used to reduce inflammation. However, to reduce negative effects of these medicines on gastric and renal function, selective inhibitors of COX-2 are administered. These drugs inhibit COX-2, an enzyme involved in the production of prostaglandins which stimulate immune cells and initate inflammation.

It has been shown that S-adenosylmethionine administered to affected individuals reduces inflammation and consequently pain and joint dysfunction like COX-1 and COX-2 inhibitors. As a result, it may improve the functioning of the osteoarticular system.

Support for male health

Testosterone, called the male hormone, is produced in testicles in the presence of luteinizing hormone secreted by the pituary gland. It has been demonstrated that SAMe and methylation reactions, in which it participates, are critical to androgen production. Their disorders leads to a decrease in testosterone concentrations which may have a negative impact on male hormonal balance.

To sum up, NOW Foods SAMe shows a wide spectrum of health benefits. It is recommended especially to persons who want to maintain healthy bones, joints and nervous and endocrine system. 

 

Out Of Stock
Since 2005
SAMe 100mg SAMe 100mg 30 tab.
NOW FOODS
13.95 $

SAMe 100mg 30 tab.

features

Fat loss:
Concentration:
Health:
Regeneration:

- Delivery even day after tomorrow

- Foreign shippment from 5.83 $ Every 85.44 $ reduces shipping costs by 2.85 $

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01709231594 (mon.-fri 900-1700)

- Delivery even day after tomorrow

- Foreign shippment from 5.83 $ Every 85.44 $ reduces shipping costs by 2.85 $

You have got questions about the product

sales@mz-store.co.uk

01709231594 (mon.-fri 900-1700)

Description
  • Influences positively cognitive functions and sleep-wake rhythm
  • Inhibits effectively inflammation
  • Has a protective effect on joint cartilage
  • Improves processes of neurotransmitter biosynthesis
  • Helpful in osteoarthitis
  • Helps control gene expression
  • Regulates testosterone release into blood
  • May help fight depression
  • Donor of methyl groups

Now Foods SAMe is the best absorbed form of S-adenosylmethionine on the market which produces far-reaching effects on many systems, improves significantly memory and focus, stabilises mood, helps combat depression and osteoarthritis, promotes a peaceful sleep and prevents inflammation.

S-adenosylmethionine is a natural substance that is a source of methyl groups. Binding and cleavage of these groups are one of the mechanisms which regulate metabolism, including the expression of specific genes. SAMe is reported to have a central effect by stabilising mood and the peripheral one by regulating bone metabolism and the endocrine system.

S-adenosylmethionine in this supplement is one of the best absorbed forms on the market. After entering the bloodstream, it is distributed in the serum in a free form (not bound to proteins) and transported to cells with the aid of SAMC.

Methionine metabolism

S-adenosylmethionine is formed by combining methionine, an indispensable amino acid found in the body only when provided from external sources (food), and ATP, a molecule synthesised during energy metabolism. Subsequently, numerous cyclic metabolic processes lead to the formation of such metabolites as S-adenosylhomocysteine or homocysteine till the end of the cycle.

High homocysteine levels have a potential atherogenic effect – it may speed up the progression of atherosclerosis. In order to prevent the formation of this compound, it is important to supplement with B vitamins – B12, folic acid and also B6, whose presence help end the cycle of methionine metabolism.

Furthermore, it has been demonstrated that SAMe supplementation does not lead to the accumulation of homocysteine and thus development of atherosclerotic plaque.

Antidepressant properties

Studies have shown that individuals with diagnosed depression suffer from SAMe deficiency in the central nervous system. This is probably caused by two mechanisms. The first one is folic acid deficiency, which was observed in a major group of study participants. The second one arises from the malfunctioning of the enzyme catalysing a reaction in which ATP is bound to methionine.

The administration of SAMe brought suprising results in comparison with tricyclic antidepressants. It has been therefore suggested that SAMe may relieve symptoms of depression.

In addition, S-adenosylmethionine is a donor of methyl groups in the synthesis of various neurotransmitters – acetylcholine, noradrenaline, dopamine and melatonin – which have an impact on cognitive functions of the body and help also modulate mood and regulate the sleep-wake rhythm.

Osteoarticular health

Persons who train hard or elderly individuals suffer often from osteoarthitis. This disease is inflammatory and leads to slow degeneration of joint cartilages, accompanied by pain and impaired mobility. Non-steroidal anti-inflammatory medicines are used to reduce inflammation. However, to reduce negative effects of these medicines on gastric and renal function, selective inhibitors of COX-2 are administered. These drugs inhibit COX-2, an enzyme involved in the production of prostaglandins which stimulate immune cells and initate inflammation.

It has been shown that S-adenosylmethionine administered to affected individuals reduces inflammation and consequently pain and joint dysfunction like COX-1 and COX-2 inhibitors. As a result, it may improve the functioning of the osteoarticular system.

Support for male health

Testosterone, called the male hormone, is produced in testicles in the presence of luteinizing hormone secreted by the pituary gland. It has been demonstrated that SAMe and methylation reactions, in which it participates, are critical to androgen production. Their disorders leads to a decrease in testosterone concentrations which may have a negative impact on male hormonal balance.

To sum up, NOW Foods SAMe shows a wide spectrum of health benefits. It is recommended especially to persons who want to maintain healthy bones, joints and nervous and endocrine system. 

 

Directions for use
Manufacturer

Composition

Composition

Container size: 30 tabletsServing size: 1 tabletServings per container: 30
per portion (1 tablet)amount%DV
S-Adenosyl-L-Methionine Disulphate Tosylate100 mg

Other ingrednients

Cellulose, Croscarmellose Sodium, Magnesium Stearate (vegetable source), Silica, Stearic Acid (vegetable source), Ascorbic Acid, Citric Acid and Enteric Coating (water, methacrylic acid, methyl methacrylate, glycerin).

 

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Methionine

Information

Exogenous methionine is an amino acid containing sulphur in its composition. It provides multi metabolism, with the indispensable help of vitamin B6. Participates in the synthesis of phospholipids (e.g. Lecithin), carnitine responsible for transport in the body of long-chain fatty acids, burned in the mitochondria cells (organelles in cells with a separate kernel), along with cystine forms cysteine. It is in the body antioxidant function. Natural source of acquisition of methionine are high-protein foods of animal origin (eggs, meat, fish), vegetable (sesame seeds, grain products). Available in all protein and carbohydrate protein and amino acid supplements such EAA and contain so-called all-day amino acids, supporting the liver preparations and cosmetics supporting the growth and condition of hair, skin and nails.


 

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