The most effective way to lose weight is to force the body to a faster and more efficient transport of fatty acids and more efficient burning of these compounds in the mitochondria. The more you intensify the thermogenesis, the better the end result will meet your expectations and assumptions. Ingredients found in the basic fat burners ie. caffeine or yohimbine, unfortunately have a tendency to raise the blood pressure. Therefore, the science went forward and created substances that can be used by people with arterial hypertension. A weight reduction in this case is also a better prognosis for this disease.