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The preparation is recommended to those who regularly practice physical activity to supplement amino acids level and increase muscle mass growth. It is most effective to use the preparation before and during training. The recommended dose is dependent on the body mass – up to 80 kg – 5 tablets; above 80 kg – 8 tablets.
Glutamine (L-glutamine) - endogenous amino acid building proteins, glutamic acid amide. In the human body it is responsible for the synthesis of proteins, acid-base balance and removing ammonia from the organism. With the shortage of energy taken from the muscle tissue, glutamine with alanine participate in the process of gluconeogenesis, and participate in the production of glucose substrate. Glutamine has a direct impact on the proper functioning of the digestive system and immune immunity of the organism. Participates in the synthesis of one of the most powerful antioxidant glutathione. It has anti-catabolic potential. It can be found naturally in foods of animal and vegetable origin, protein supplements. Used as mono- or multi-component amino acid supplements, and supplements improving biological recovery after exercise, often in combination with BCAA.
Dosage: 5-20 g per day (portioned during the day, and after training and waking up). The supplementation uses the minimum dose of 2-15g to 1 serving.
Alanine is an endogenous amino acid (i.e. having the ability to synthesize the human body other amino acids and pyruvate), building up protein. It has a key role in the transport of nitrogen between the muscles and the liver (i.e. Cahill cycle). It allows to transform glucose in non-sugar compounds. During prolonged exercise it enhances metabolism. It occurs in products of animal origin (meat, dairy, eggs) and vegetable origins (legumes, peas). It is used in the form of amino acid supplements in pre- and post-workout preparations. It complements the BCAA. Increased use of supplements with alanine is required in athletic training when high strength and endurance is required (e.g. weights lifting athletes marathon runners etc.).
Proline - endogenous amino acid, one of the 22 amino acids building proteins. As a result of the conversion (carried out with the participation of vitamin C) in the form of hydroxy-proline, it is the ingredient of collagen ( basic protein of connective tissue). Influences positively the locomotor system especially in people exposed to an overload (e.g. strength and endurance sports athletes) and during rehabilitation after injury or surgery of locomotor system organs. It is naturally occurring in food, or is synthesized in the body from glutamate. In the dietary supplementation it is a component of high-protein nutrients, amino acid products (in the form of proline or hydroxy-proline), and supporting the functioning of the locomotor system that contains collagen available at www.muscle-zone.pl.
Dosage: No standards for use. Dosage as customarily in supplementation
Glycine is belongs to 22 essential amino acids (synthesized within the body) constructing proteins, and non-protein component of enzymes i.e. heme. It is a inhibiting neurotransmitter allowing for improvement in sleep comfort even at a dose of 3 g at bedtime. Glycine (as arginine) is a precursor of creatine. It is essential for the synthesis of a strong antioxidant - removing free radicals out of the body - glutathione. It is cholagogic and cholepoiteic. By interfering with the synthesis of growth hormone, accelerates the biological recovery of an organism. Naturally present in foods of plant and animal origin. In the sports supplementation is a component creatine stacks, amino acid supplements, protein supplements based on natural ingredients and carbohydrate and protein.
Lysine belongs to the group of 9 essential amino acids delivered into the body from outside (with food or as a supplement) .It is a building substance of protein (the muscle protein). It is available in food of animal origin (meat, dairy products) and vegetable (legumes). It plays an important role in many physiological processes (absorption of calcium, production of enzymes, hormones and antibodies), and arginine is a component of supplements that increase the synthesis of growth hormone (HGH stimulators). In the form of hydroxylysine (a component of collagen) recommended for the treatment of sports injuries, and prevention. In the case of stress and excessive physical and psychological overloads, it is recommended due to the function of lowering cortisol levels. Also it applies in medicine, in the treatment of anxiety and herpes. The share of lysine intake of daily doses of amino acids should not exceed 5.1%. Available for purchase at www.muscle-zone.pl.
In the processes of digestion of protein matter, as a result of decarboxylation of lysine, may be converted into cadaverine (biogenic amine) having a strong toxicity.
Dosage: the lack of a well-defined standard daily intake of lysine. The supplementation dosages regularly used: with arginine 500 mg - 2g (before bedtime) pre- and post-workout optionally with other amino acids.
Valine – is a branched essential amino acid, indispensible for the functioning of the nervous system (receiving of sensory information), involved in muscle protein synthesis and energy generation. Administration of additional doses of valine before exercise (or immediately after) has anti-catabolic effect, protecting the proteins and allowing them to rebuild. It is slightly stimulatory (delays symptoms of fatigue during workout), affecting the level and relations of neurotransmitters. It helps to protect the liver. It stimulates an increase in strength and muscle mass, participates in the reduction of body fat. BCAA, EAA, and other mixtures of amino acid supplementation, protein and protein supplements and carbohydrate-stacks, brings positive results in strength and endurance sports.
Valine deficiency can occur in case of increased energy needs of the body, as the result of stress and too much stress load.
BCAA are three essential amino acids having a side branched aliphatic chain (isoleucine, leucine, and valine) and a similar course of metabolic processes, occurring in the muscle tissue. In its natural form, they are found in high-protein animal foods (i.e. beef, milk proteins). BCAA have the anti-catabolic and anabolic potential. They support energy carriers during the energy crisis and affect the functioning of the nervous system (eliminate stress, reduce fatigue), hormone activity and kinases, which are responsible for the metabolism of proteins. In the sports supplementation they are used as supporting elements of exercise capacity (strength and endurance) and post-workout recovery; also as anti-catabolic and catalyst of anabolic changes. Taking BCAA after exercise almost immediately restores the levels of these amino acids in the blood (excluding liver) and supplies the muscle tissue. Leucine activates of mTOR kinases (starting anabolism of muscle proteins) and has the intensified effect with insulin, which acts on the PI3-kinase and protein kinase B. Branched amino acids chain BCAA, willingly used by strength, strength-endurance and endurance athletes, they are available in the form of single-component supplements, and advanced amino acid supplements, creatine, pre- and post- training stacks, and isotonic drinks.
Dosage: usually 1-2 grams of BCAA per 10 kg of body weight per day. Mainly before and after training.
Arginine is an exogenous amino acid, it is a component of dietary proteins, not always synthesized in the human body in necessary quantity, so it is necessary to deliver it in the form of synthetics. It takes part in the biosynthesis agmatine, creatine and nitrogen oxides. The use of supplements containing arginine before workout increases the exercise capacity (strength, endurance). Used after considerable effort intensifies the transfer of energy and building compounds and intensifies the process of recovery. Used at bedtime in combination with lysine and ornithine enhances the synthesis of growth hormone. takes part in the intrasystemic synthesis of creatine. Arginine (as a precursor of ornithine) is involved in the urea cycle, increases the flow of blood in the circulatory system, increases sexual potency (in a short time after application). It affects the body's immunity preventing infections, and lowers blood pressure. In supplements – usually as alpha-ketoglutarate.
Threonine - essential amino acid, or synthesized from food or (and) in the form of supplements. It takes part in the production of new muscle proteins. It is essential for the proper formation of the immune system is maintained in good condition the skin, bones. It affects the normal development of the enamel of teeth and the digestive system by acting positively on the liver and gastric mucosa. It is essential to the proper functioning of the nervous system. On the Polish there are no threonine mono-preparations. Available in the form of blends of amino acids (e.g.the type of EAA) and natural protein supplements.
Deficiency of threonine can cause neurological disorders and increased depression.
Dosage: the lack of standards of daily demand threonine. Doses customarily used in the supplementation.
Isoleucine is an essential branched amino acid (BCAA), leucine-isomer. It has anti-catabolic action ( protects muscle against decay), glucogenic (an alternative energy source when the level of glucose after exercise decreases, helps for the regulation of blood glucose levels, reduces the deficiency of fatty acids), anti-catabolic (muscle protects against decay), reduces stress. It participates in the synthesis of proteins (including the synthesis of hemoglobin). It is an essential part of the regeneration of damaged tissues of the body, and after intense training. It occurs in products containing animal protein (meat and dairy products, eggs, dairy products) and plant (almonds, walnuts) and dietary supplements.
Isoleucine is applied with other branched chain amino acids: leucine, valine, and in the supplement complex type of BCAA, in the proportions: leucine: isoleucine: valine = 2: 1: 1. The supplements used in competitive sports requiring increased strength, the bigger share of isoleucine is used.
Dosage: No standard daily use. Frequently applied directly after the workout during the decrease of the glucose level of or at fatty acid deficiency.
Asparagine is an endogenous amino acid, synthesized directly in the human body, and also in foods containing high amounts of plant and animal protein. It is also available as nutrients, supplements and mineral preparations (e.g. Magnesium or zinc aspartate [ZMA]). It participates directly or with support of synthetics in physiological processes: energy conversion, synthesis of purines and urea. Its derivative (asparagine) with phenylalanine (exogenous amino acid) is a part of aspartame [E-951]. There is more and more positive feedback from athletes about the usefulness of its equivalent d-aspartic acid to increase the of testosterone potential.
Dosage: the lack of standards for daily consumption
Exogenous methionine is an amino acid containing sulphur in its composition. It provides multi metabolism, with the indispensable help of vitamin B6. Participates in the synthesis of phospholipids (e.g. Lecithin), carnitine responsible for transport in the body of long-chain fatty acids, burned in the mitochondria cells (organelles in cells with a separate kernel), along with cystine forms cysteine. It is in the body antioxidant function. Natural source of acquisition of methionine are high-protein foods of animal origin (eggs, meat, fish), vegetable (sesame seeds, grain products). Available in all protein and carbohydrate protein and amino acid supplements such EAA and contain so-called all-day amino acids, supporting the liver preparations and cosmetics supporting the growth and condition of hair, skin and nails.
Serine belongs to the group of essential amino acids, which is synthesized in the human body, found naturally in the human brain, and soy milk. Its derivative is Phosphatidyl serine. Serine is involved in the synthesis of muscle proteins, it includes activator of protein kinase C (an enzyme localized in the brain), acting positively on the nervous system (improves the functions of association and memory and concentration), increases the ability to receive external stimuli and intensifies the process of information processing. Serine used in food reduces the level of the hormone cortisol located in the catabolic muscle, affecting adversely the metabolism, resulting in a decrease in muscle mass and fat gain. The use of serine affect the rate of convalescence, recovery after injuries and maintaining psychophysical condition. Due to the high price, in supplementation used very rarely. Preparations available at www.muscle-zone.pl
Dosage: as usually used in supplementation
Leucine is an essential amino acid, one of the three branched chain amino acids, ketogenic, its isomer is isoleucine. It affects the secretion of anabolic hormones (insulin, combined carbohydrates), acts on enzymes (mTOR) starting the process of muscle protein synthesis and controlling its course. Protein synthesis by leucine is affecting the development of bones, muscles and skin. It reduces the fat tissue. Without the availability of leucine, protein synthesis is impossible. It naturally occurs in animal products (such as eggs, meat, dairy and fish), plant origin, and as a post-training supplements, BCAA, EAA, no-boosters, creatine stacks, carbohydrate supplements. Ir is also in the form of mono-preparation supplements. It is one of the most important amino acids for the athlete's body, basically in every sports discipline.
Dosage: The demand is 5-10 g / 24h, dosage pre- and post-workout and in the morning after waking up.
Phenylalanine (essential amino acid) is provided from the outside with food or synthetic products. Its source are the high-protein foods and supplements, concentrates: protein, amino acid and nutritional supplements for athletes. Precursor of tyrosine, thyroid hormones and neurotransmitters (adrenaline, noradrenaline, dopamine), phenylethylamines (neuromodulator) and melanin pigments of hair and skin. Essential for the proper functioning of the nervous system. It has analgesic, antidepressant, and is used as an additive to supplements with thermogenic and stimulating action. It is a component of aspartame.
Excess phenylalanine consumed by people with neurological problems, may reduce the availability of other essential amino acid tryptophan of nervous system and consequently lead to a reduction in serotonin and exacerbate the depression.
Tyrosine - endogenous amino acid (synthesized within the body), one of the 22 protein amino acids building. It occurs naturally in animal food products (eggs, dairy, meat). If the deficiency, it can be synthesized by hydroxylation of phenylalanine, capable of being converted to tyrosine in the liver. It is a precursor of neurotransmitters: dopamine (the group of catecholamines, participating in the processes occurring in the nervous system, causing muscle coordination and participates in the synthesis of many hormones) and noradrenaline (counteracting stress, stimulating the heart and circulatory system, and increasing glycogenolysis and lipolysis participating in the processes of energy transformations). Tyrosine is a precursor of thyroid hormones responsible for the rate of change in metabolic processes and pigment (melanin). In the supplementation, preparations containing tyrosine are used in programs reducing body fat (weight loss), improve mood and are stimulants.
Dosage: Customarily 500-2000 mg per day.
Histidine is one of the 22 amino acids being part of protein - depending on the source of information it is referred to as "relatively exogenous" or "exogenous". The required dosage of this amino acid is very small, and at the same time it should be added that the intestinal microflora can also play a role in meeting the demand for it.
Histidine is a precursor of carnosine, and therefore dipeptide having antioxidant and buffering qualities. Increasing the dose of carnosine in muscles is an effective way to increase strength and endurance, as well as to accelerate recovery after exercise, thus improving the indicators that are extremely important especially in the case of people being engaged in regular physical activity , including professional athletes.
The number of products containing histidine and available on the market is quite limited. This amino acid is mainly added to some of the supplements used before and/or after exercise, as well as to some of the amino acid supplements. It should be noted, however, that it also occurs naturally in foods rich in protein, and thus primarily in meat, eggs and dairy products, as well as in protein supplements.
Histidine is an amino acid which can be converted in the body into glucose. It also takes part in the synthesis of proteins, including hemoglobin.
Dosage: There are no precise data, but as it has already been hinted above - the required dosage of this amino acid is very small.
Tryptophan is one of the nine essential amino acids that require high protein food consumption, mono-preparation supplements tryptophan, an amino acid type and EAA-day nutrients and protein, which is essential in the process of protein synthesis. A derivative of 5-HTP in the decarboxylation is a precursor of serotonin ((tissue hormone having an effect on blood pressure and peristalsis), and the subsequent processes of melatonin (the hormone sleep). It is used for synthesis of nicotinic acid (niacin, known as vitamin PP). The due to the appetite suppressant is also used in certain weight loss formulations.
Even a small deficiency is dangerous for the course of many physiological processes, can cause the nervous system deterioration of mood, insomnia, and disturbances in the digestive process. Tryptophan deficiency in the long term leads to depression and neurological disorders.
Mono-preparation supplements of tryptophan are recommended as a means of reducing the stress and reducing the feeling of insomnia. A part of the nutritional supplements type of EAA and all-day aminoacids, it is a valuable component of protein supplements. Available in store www.muscle-zone.pl
Doses recommended in supplementation: 500 - 2000 mg at bedtime, alternatively 500 - 1000 mg before meals.
Cysteine belongs to the group of essential amino acids, synthesized by the body, involved in detoxification of the body. The combination of L-cysteine with glutamine and glycine is involved in the synthesis of glutathione (a powerful antioxidant) and the proteins, enzymes and co-enzymes. Present in the protein product, in smaller amounts in corn and peanuts. The source of the acquisition are also concentrates and whey protein isolates, and preparations containing mixtures of amino acids. Not in the form mono-preparations. It is a component of detoxification, supporting the work of the liver supplements and in supplements improving the cosmetics of the body, usually in the form of L-cystine (two connected cysteine particles) or in the form of NAC.
Dosage: the usual supplementation: 50-500 mg per day.
Taurine – non-protein amino acid containing sulphur, which is synthesized in the body from methionine and cysteine, present in sufficient amount in human or animal body (in the brain, heart and skeletal), although in some cases must be supplemented. Significantly affects the calcium content in the cells and stabilizes the water and electrolyte balance and maintains acid-base balance. Takes part in the synthesis of bile acids. In the body acts as a neurotransmitter and neuromodulator. It is an insulin-mimetic improving insulin metabolism, responsible for transport of nutrients (such as amino acids, glucose, creatine) to the cells and muscle tissue. These properties determine that it is a valued mono-preparation supplement and valuable addition to creatine and amino acid supplements, recommended for psycho-pchysically active people and athletes and other competitive sportsmen in pre- and post-workout periods.
Dosage: 3 grams per day.
Ornithine belongs to endogenous non-protein amino acids, it is produced by transformation of the amino acid arginine and glutamic acid. It is an intermediate in a metabolic cycle urea synthesis from ammonia and carbon dioxide. The degradation of amino acids in the liver making the first removes nitrogen (alpha amino groups are transferred to alpha-ketoglutarate) and leads to the formation of glutamate, transformed into the form of ammonium ions. It is necessary to neutralize the highly toxic ammonia, which is carried out by aspartate, creating argininosuccinate. A further phase of change is the formation of arginine and fumarate. Then the cycle is repeated. In the transition process, ornithine is the starting material for the enzyme that catalyses a particular stage of the urea synthesis. It is also an acceptor for the synthesis of citrulline. Ornithine, through the synthesis of polyamines, has a regenerating effect on the liver.
Ornithine is available as mono-preparation (often included with the other ingredients of supporting liver function) and multi-component supplements containing ornithine aspartate. Indispensable in sports supplementation in no-boosters (pre-workout products) as it stores the arginine, it slows down its expenditure and allows for more effective use in the synthesis of nitric oxide. Available in the full range at: www.muscle-zone.pl
Dosage: There are no specific standards for daily consumption. 200 - 1500 mg / 24h, commonly used in supplementation.