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Some individuals may not respond well to methylated forms of vitamins. They should find another complex based on non-methylated form of vitamin B9 and B12.
Due to the ability to increase energy levels, the supplement may cause sleep problems. Because of that, it is not recommended to take it in the evening.
Benfothiamine - a highly bioavailable form of thiamine, also called vitamin B1. According to various sources, the advantage of its absorption over other forms of thiamine may be even of several times. Apart from this, thanks to its properties to dissolve in fats, it demonstrates high affinity to nervous tissue, as a result of better permeability through neuronal lipid membrane. Thanks to this, benfothiamine is indicated as the form of vitamin B1, which is the most suitable for people dealing with problems of the nervous system, which is the consequence of improper supply of thiamine. It positively influences energy metabolism of neurons.
Benfothiamine is also indicated as a supplement, demonstrating positive influence on the treatment of symptoms of diabetes complications. It contributes to reducing neuropathy and retinopathy and decreases related pain symptoms. It also limits the pace of the process of protein glycation and supports carbohydrate metabolism of patients.
Supplementation with vitamin B1 should be of interest to people who use proton-pump inhibitors and diuretic drugs.
Vitamin B2 (riboflavin) is soluble in liquids, is involved in the metabolism of proteins, fats and carbohydrates. Required for growth of the organism. Takes part in the production of erythrocytes (red blood cells). It is located in natural foods, such as yeast, meat (especially liver, kidney, heart), milk, fish and green leafy vegetables.
A deficiency of vitamin B2 inhibits the growth, diseases of the mouth, loss and greasy hair, seborrhea and stratification of nails. Increases skin roughness and susceptibility to acne and oily skin.
Dosage: 1-2 mg per day.
Vitamin B3 (vitamin PP, niacin, nicotinic acid, nicotinamide) is niacinamide niacin. It is used in interaction with vitamins B1, B2 and B6 in the synthesis of hormones during lactation. It provides proper functioning of the brain and nervous system. It is helpful in inflammatory conditions of the skin. Required for synthesis of sex hormone, estrogen, testosterone, cortisone, and insulin. It does not lose its properties in the manufacturing and storage. The source of acquiring vitamins PP are both products of animal origin (the lean meat, eggs, fish) and vegetable origin (dates, figs, hazelnuts, plums).
Dosage: 2-12 mg / day for children, 14 mg / day for women, 16 mg / day for men and 17-18 mg / day for pregnant or nursing women.
Inositol hexanicotinate (IHN), also known as inositol hexaniacinate, is the inositol esterified with niacin.
IHN undergoes hydrolysis in the body, gradually releasing nicotinic acid and inositol. Such properties make this form not only very effective but also free of the side effect referred to as flush effect (redness mainly on the face, forearms and neck), which occurs in standard forms of niacin and is very unpleasant for many individuals.
Inositol hexanicotinate is a component of niacin-based dietary supplements. It is suggested that inositol hexanicotinate is as effective as niacin alone (may contribute to lowering cholesterol levels). Because of decreased risk of such symptoms as skin redness, itching and tingling, it can be a perfect solution for persons who resign from traditional vitamin B3 supplements due to these unpleasant effects.
Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
Pyridoxal 5-phosphate (P-5-P) - the form of vitamin B6, called coenzymatic, considered the best assimilable form of this vitamin by the human organism. This is related to direct metabolic activity of pyridoxal-5-phosphate in the human organism. It does not have to be subjected to biochemical transformations in the organism in order to be able to enter metabolic pathways as a biologically active ingredient.
Vitamin B6 is an incredibly important factor regulating the work of many processes in the organism due to its role in the organism as a coenzyme, essential for the activation of many important enzymes. Thanks to this, it regulates metabolism at many levels and its proper supply is conducive to maintaining homeostasis of the organism.
Another aspect of effectiveness of vitamin B6 is its influence on the normalization of emotional states. It is conducive to relaxation, facilitates falling asleep and falling in a deep, the most valuable sleep. Special influence on P5P on the psyche is proven in women before menstruation, as it demonstrates considerable ability to reduce the symptoms of the pre-menstrual syndrome.
Supplementation with vitamin B6 also demonstrates positive influence on the functions of the nervous system. It is conducive to the nourishment of neuronal tissues and optimizes the secretion of neurotransmitters, thanks to which it promotes nervous transmission and demonstrates neuroprotective properties. It was proven that vitamin B6 may decrease the risk of developing Parkinson’s disease.
Some sources also suggest the ability of pyridoxal 5-phosphate to reduce the risk of cancer. This effectiveness is noted especially in relation to breast cancer.
Quatrefolic is the glucosamine salt of (6S)-5-methyltetrahydrofolate and also an active form of folic acid. It is an innovative nutrient (fourth generation folate) which is well soluble in water and thus absorbed effectively by the body. As an organic compound ranked among B vitamins, it is necessary for normal functioning at the cellular level.
Adding folates to a diet is recommended especially to pregnant and lactating women. These compounds may contribute to healthy foetal development. According to studies, their intake may reduce the incidence of pregnancy complications.
Some sources report that folate supplementation supports cardiovascular function (blood production) and contribute to healthy immune function.
Quatrefolic may affect the metabolism of homocysteine whose levels increase in the body over time. Adding it to a diet may thus prevent the development of dementia and maintain healthy cognitive functions which is vital to adults, especially the elderly.
What is 5-methyltetrahydrofolate (5-MTHF)?
5-methyltetrahydrofolate (5-MTHF) is a methylated, biologically active form of folate. It is especially willingly used by people with folic acid metabolism disorders, especially by polymorphisms of the gene coding the production of methyltetrahydrofolate reductase. Using this form allows to skip narrow gorge created by this polymorphism and enjoy all effects induced by folates. It is also a good substitute for synthetic folic acid (pteroylmonoglutamic acid), which in clinical trials demonstrates the ability to increase the frequency of developing cancers.
Folates, also called vitamin B9 have a wide contribution to the development of the nervous system. They contribute to converting homocysteine to methionine and then to s-Adenosyl methionine, which is the main donor of methyl groups. Thanks to this, the condition of the circulatory system is increased, as the amount of pro-inflammatory homocysteine is decreased and the intensity of the production processes of creatine and neurotransmitter synthesis is higher, which is reflected in the reduction of fatigue and better psychological condition.
5-MTHF in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
Salt (sodium chloride, or table salt), natural source of electrolytes (chlorine and potassium), regulating water and electrolyte and acid-base balance of the body, affecting the nervous system and blood pressure. Sodium is an essential element for the proper growth. The proper dose of salt prevents overheating of the body and solar stroke. It provides the proper functioning of muscles and nerves the body. Chlorine in combination with sodium, is involved in the digestive process and maintains acid-base balance in the body, as antitoxin removes toxic products of metabolism in the liver. Salt is a flavour component and preservative of many foods, nutritional supplements and mixtures of electrolytes, available at www.muscle-zone.pl
Dosage: no specific standards of consumption, used so as to provide sufficient amount of electrolytes to the body (sodium and chloride).
Vitamin B12 (cobalamin, cyanocobalamin) is a vitamin soluble in liquids. Participates in the production of red blood cells and is essential in the absorption of iron by the body. It calming effect, a positive effect on concentration and memory. Intensifies its action in cooperation with folic acid (vitamin M). Usually occurs in animal products, fish and dairy products. It contains trace elements.
Vitamin B12 deficiency can lead to pernicious anaemia, general and immunity weakness, inhibiting of growth and damage to the myelin sheath of nerves.
What is methylcobalamin?
Methylcobalamin is a biologically active form of vitamin B12. It is one of the two forms of this vitamin that may be used as cofactors in various reactions. It differs from popular cyanocobalamin in the presence of methyl group instead of cyanide, thanks to which it releases the organism from the need of neutralizing this harmful factor.
The methyl group from methylcobalamin may be transferred to homocysteine, thanks to which it comes back in the form of methionine in order to be further converted to SAMe, which is the main donor of methyl groups in our organism. These methyl groups may be then used in the processes of creatine production, in neurotransmitter metabolism and as DNA methylation, thanks to which we achieve proper energy level, better well-being and generally better condition of the organism. B12 is a coenzyme for three enzymes: isomerase, methyltransferase and dehalogenase.
Apart from the influence on the nervous system, the supply of vitamin B12 is also very important for the proper synthesis of red cells as well as hemoglobin and anemia prevention.
Methylcobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
Biotin (vitamin H, co-enzyme R) is in a group of B vitamins, due to the presence of sulphur compounds it is involved in the synthesis of ascorbic acid (vitamin C). Also synthesized in the intestines. It enhances the production of hormones and regulates cholesterol levels. It reduces muscle pain. It prevents hair loss and graying of hair. It soothes the skin inflammations. No toxic effects. Often combined with other B group vitamins and vitamin A. The natural sources of biotin are: whole grain bread, yeast, eggs (yolk), milk, brown rice and cheese.
Daily demand: 100-300 mg per day
Choline belongs to the soluble in liquids group of B vitamins. It is an organic nitrogen base containing lecithin, and acetylcholine. Together with inositol is involved in the metabolism of fats and cholesterol metabolism, preventing its accumulation on the walls of arteries and deposits in the gallbladder. With the penetration of the brain, contained lecithin improves its action and improves memory. Used in the treatment of age-related diseases (Alzheimer's). It occurs in plant foods: yeast, wheat germ, lecithin, green leafy vegetables and egg yolks.
Choline citrate is a combination of choline with a derivative of citric acid. It is a new form of choline which comprises about 51% of this substance. This means that 1 g of choline citrate corresponds to about 500 mg of choline. Because of that, it contains more choline than e.g. bitartrate.
Choline citrate does not only provide choline but also has one of acetyl groups necessary for the production of acetylcholine – the main neurotransmitter in the central nervous system that is extremely important for normal thought processes and supports cognitive functions.
Choline citrate is combined usually with a more sweet ingredient to neutralise its sour taste. It is available in the form of monopreparations and also as a component of multi-ingredient dietary supplements targeted at improving focus, motivation and psychomotor skills.
Para-aminobenzoic acid (PABA) is soluble in water, part of the vitamin B complex. Synthesized in the body. Participates in energy conversion (metabolism) of proteins. Used in ointments to prevent excessive sun exposure, protecting against ultraviolet radiation. Positive effect on the condition of the skin and hair. According to a recent study, in conjunction with folic acid, allows to restore hair natural colour on gray. Synthesized in the body. Natural source of acquisition are: brewer's yeast, wheat germ, bran, whole grains, and rice and products of animal origin: liver and kidneys.
Dosage - the lack of strict standards daily dose
Inositol is an organic compound from the group of B vitamins soluble in fluids, present in the natural or synthetic form, synthesized in plants, such as brewer's yeast, beans, grapefruit, cabbage, sprout of wheat, melons and animal (liver). Along with choline is included in the lecithin. It affects the cell nutrition of the central nervous system (brain) by reducing the level of LDL (bad cholesterol), this makes it applicable in treatment of Alzheimer's disease and atherosclerosis. It has a calming effect. There has been a beneficial effect of inositol on the skin and hair reported.