One capsule contains a very high dose of vitamin B12 in its active form, so one portion a day should be definitely enough in most cases, for therapeutic purposes as well. Such a high dose is worth taking until the deficiency is supplemented or the parameters that weren’t satisfactory before supplementation are improved. Then the dosage can be reduced.
For better absorption, it’s best to take a capsule with water after a meal. The indications for using this supplement are low mood, chronic fatigue, concentration problems, irritability. It can prove very efficient in megaloblastic anaemia. Supplementation should be particularly interesting for people who struggle with digestion and absorption problems.
What is methylcobalamin?
Methylcobalamin is a biologically active form of vitamin B12. It is one of the two forms of this vitamin that may be used as cofactors in various reactions. It differs from popular cyanocobalamin in the presence of methyl group instead of cyanide, thanks to which it releases the organism from the need of neutralizing this harmful factor.
The methyl group from methylcobalamin may be transferred to homocysteine, thanks to which it comes back in the form of methionine in order to be further converted to SAMe, which is the main donor of methyl groups in our organism. These methyl groups may be then used in the processes of creatine production, in neurotransmitter metabolism and as DNA methylation, thanks to which we achieve proper energy level, better well-being and generally better condition of the organism. B12 is a coenzyme for three enzymes: isomerase, methyltransferase and dehalogenase.
Apart from the influence on the nervous system, the supply of vitamin B12 is also very important for the proper synthesis of red cells as well as hemoglobin and anemia prevention.
Methylcobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
Folic acid - also known as vitamin B9, is a synthetic form of naturally occurring folates. It needs to be transformed to folates in order to be biologically active also in the human organism. Therefore, its supplementation is recommended to people who do not have problems with methylation processes.
The majority of people associate folic acid with the period of pregnancy. It is definitely a justified association. Proper supply of vitamin B9 conditions correct development of the fetus and prevents disorders of neural tube defects in a baby.
Supplementation with folic acid also demonstrates positive influence on the functions of the nervous system of adults. Some sources say that it is conducive to maintaining beneficial emotional states. Moreover, folic acid takes part in the process of erythropoiesis, thanks to which it enables efficient production of red cells.
Supplementation with folic acid should be also considered by men who deal with low sperm quality. It was proven that complementing the level of vitamin B9 is conducive to increasing reproductive abilities of men.