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In order to increase its effectiveness, you may combine the preparation with e.g. L-carnitine. However, do not use the preparation while eating a raw egg, as it contains avidin, which may contribute to lowering alpha lipoic acid (ALA) absorption. What is important, even though ALA is a compound soluble in fats, it does not have to be used during a meal with its high content, as it is very well absorbed in the intestines and may be also used on an empty stomach.