Leucine, isoleucine and valine must be supplied in appropriate quantities and proportions in order to provide their optimal performing. The additives also play important role. Alanine, which is rarely supplemented on its own, when added to BCAA, provides ideal conditions for the use of these amino acids in metabolic processes (through its effects on glucose-alanine cycle). All the insulin-mimetic substances should be also considered, as they are operating in a similar way to insulin, which, similarly to this hormone, have got very positive influence on the sensitivity of all cells, and thus the use of substances running in the bloodstream. Insulin-mimetic can be substances like: d-pinitol, inositol or cinnamon.