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The supplement is relatively safe, therefore in order to maximize the effects, a daily dose may be increased. In case of any discomfort in the digestive system, divide a single dose into several portions during the day, as some ingredients of the preparation may irritate intestinal mucosa.
In order to achieve maximal effect of the preparation, it needs to be taken for the period of at least 4 months.
Additional supplementation with vitamin B6 and niacin will allow to facilitate the work of enzymes, necessary to synthesize collagen.
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Collagen hydrolyzate (FORTIGEL) obtained by enzymatic hydrolysis of collagen, which is a major ingredient, building up connective tissue (tendons, ligaments cartilage, bone, and blood vessels), from the group of fibrous proteins (i.e. fibrous scleroproteins). Patented formula of collagen hydrolyzate, forming amino acids (such as proline, glycine, hydroxyproline and hydroxylysine) connected by peptide bonds. It is a substance easily digestible and well assimilable . Recommended in sports supplementation and for people, who are particularly active, as well as during convalescence after injuries and certain diseases.
Dosage: 10-20g per day (normally used in supplementing).
MSM (Methylsulfonylmethane) - dimethyl sulfoxide derivative, wherein the sulphur content is as by creating structural bonds sylfhydrylowych stabilize the protein particles and ensuring the proper functioning of the tissue and its biological regeneration. MSM has anti-inflammatory activity (within the connective tissue, mucous membranes and digestive disorders). In the sports supplementation recommended for people with special physical activity and during convalescence after injuries. Also used in the prevention of treatment of diseases of old age. Available in multiple formulations, also containing chondroitin, hydrolyzed collagen, hyaluronic acid, extracts of vegetable dyes (turmeric), extracts of ginger root, ascorbic acid and minerals to support the functioning of the locomotor system.
Dosage: 250-1000 mg daily (customarily taken in sports supplementation).
Glucosamine sulphate (glucosamine) is an amino sugar present in cartilage matrix; compound needed for the glycosaminoglycans and proteoglycans, affecting its structure and flexibility, increasing immunity to overloads. Glucosamine is synthesized in the human body, it can be supplied from the outside (a component of shells of marine crustaceans, and in coatings for fungi) as supplements. Increased demand for glucosamine occurs in sports training (athletes exposed to overload the musculoskeletal system), during convalescence after injuries and contusions, moreover, in the case of older people in prevention and therapeutic of degenerative changes of the locomotor system. Glucosamine occurs as mono-preparation or multiple preparations (including, among others, hyaluronic acid and chondroitin, collagen hydrolyzate and ascorbic acid) in supplementation in supporting the functioning of the musculoskeletal system, such as d-glucosamine sulphate 2KCl; HCL Poly NAG.
Dosage: 500-1500 mg per day.
Proline - endogenous amino acid, one of the 22 amino acids building proteins. As a result of the conversion (carried out with the participation of vitamin C) in the form of hydroxy-proline, it is the ingredient of collagen ( basic protein of connective tissue). Influences positively the locomotor system especially in people exposed to an overload (e.g. strength and endurance sports athletes) and during rehabilitation after injury or surgery of locomotor system organs. It is naturally occurring in food, or is synthesized in the body from glutamate. In the dietary supplementation it is a component of high-protein nutrients, amino acid products (in the form of proline or hydroxy-proline), and supporting the functioning of the locomotor system that contains collagen available at www.muscle-zone.pl.
Dosage: No standards for use. Dosage as customarily in supplementation
Chondroitin sulfate has chondroitin in its composition, belonging to the glycosaminoglycans, affecting the maintenance of joint stability and strength (building component of cartilage). Chondroitin sulfate proteins involved with the synthesis of proteoglycans. It is synthesized in the body or delivered in the foods of animal origin (e.g. containing tissue). It is used by athletes in the disciplines greatly aggravating the locomotor system with exercises, as well as in the treatment of sports injuries and joint recovery and rehabilitation after injuries, increased demand also occurs in people of advanced age. In the sports supplementation is a component of multi-component combined supplements, often containing hyaluronic acid, glucosamine and hydrolysed collagen, supporting the functioning of the locomotor system.
Dosage: 500-1500 mg per day.
Omega-3 (n-3) group of unsaturated fatty acids: short-chain (linolenic acid, belongs to the EFAs [essential fatty acids]) and long-chain (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]). The number 3 indicates That the last double bond in the carbon chain is the third from the end of carbon. Acids from the group of Omega-3 are essential components of cell membranes, they are biological precursors and activators of eicosanoids. EFAs quite abundantly supplied in food, and it can be supplied with food. EPA and DHA (oils, fats marine fish) are Supplied by foods of sea origin (sea fish and seafood). They are developed also in the human body as a result of processes of denaturation and elongation of alpha-linolenic acid , but in an amount insufficient for the full needs of the organism. Therefore,they should be supplied from the outside. With the use of so-called. western diet, supplementation of fatty acids Omega 3 is more desirable (than Omega 6).
Supplementation of fatty acids of Omega 3 is recommended for people who are physically active in order to supplement and to prevent deficiencies in body as well as due to their impact on the body composition and aerobic capacity, and tissue regeneration. In addition, it regulates the systems: circulatory (including heart), nervous, respiratory and locomotor. Formulations containing EPA and DHA are a complement to an effort diet, regardless of the degree of training and exercising.
Dietary fatty acids Omega 3, in principle, are produced in the form of capsules in combination with vitamin E as an antioxidant, available for purchase at: www.muscle-zone.pl
Dosage usually we recommended supplements in sports: depending on the supply of diet and intake of Omega 6 it is 1 - 5 g of EPA and DHA / 24 h.
EPA (eicosapentaenoic acid) – what is it?
EPA (eicosapentaenoic acid) is a long-chain, polyunsaturated omega-3 fatty acid. The chain of the fatty acid consists of 20 carbon molecules, and the first bound out of five double bounds is located at the third carbon from the omega end, which is characteristic for omega-3 acids. It is present in large quantities in fish oils, where it is accompanied by docosahexaenoic acid (DHA).
EPA is a precursor to prostaglandins and other eicosanoids, which contributes to the reduction in inflammations. It is involved in inhibition of platelets aggregation. It contributes also to the reduction in triglycerides level in blood. EPA block the activity of an enzyme, phospholipase A2, present on cell membranes, which under the influence of stressors can release polyunsaturated fatty acid (from the group of eicosanoids) into the glycerol skeleton. To some extent, EPA can be also converted into 22-carbon DHA. The both acids have positive impact on the condition of the nervous system and cardiovascular health.
Eicosapentaenoic acid contained in dietary supplements with omega-3, which are available in the offer of muscle-zone.pl
DHA (docosahexaenoic acid) - acid of omega-3 family, unsaturated fatty acids with the last double bond in the chain located on the third carbon atom from the end. Synthesized in the human body to eicosapentaenoic acid, or retrieved from foods of marine origin (fish, particularly salmon). In the medicine it is indicated for the treatment of depression, Alzheimer's ADHD. There has been its positive impact on the insulin metabolism noted as well as on endocrine and cardiovascular systems. When used in appropriate doses, it has a beneficial effect on the composition and appearance of the body. In the the supplementation it is part of formulas containing fish oil, which fill in the gaps of unsaturated fatty acids Omega 3, recommended for people with different physical activity.
Dosage: 200-2000 mg per day
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Magnesium (element from the group of alkaline earth metals, atomic no. 12, a chemical symbol - Mg), one of the most important health microelements, participates in the synthesis process of the disintegration of high energy compounds and processes of transformation of hydrocarbons and fats. It affects the dilation of blood vessels and lower blood pressure, prevents hypercoagulable state. Shortages affect cardiac arrhythmias, malignant muscle cramps, insomnia and anxiety. It is a component of many dietary supplements and found in foods such as whole grain bread, legumes, buckwheat, rice, fish, meat, as well as chocolate, cocoa and nuts.
Dosage of 100 - 500 mg / day
Magnesium citrate is a salt of magnesium and citric acid. It constitutes one of the best assimilable forms of magnesium, which plays many important functions in the organism. It is responsible, among others, for the proper work of the nervous, immune and muscle systems.
Magnesium has calming effect by decreasing the excitability of nerve cells. Thanks to introducing this element to a diet, we may potentially improve sleep quality and reduce the level of stress.
Positive influence on the circulatory system is another feature of magnesium. It prevents hypertension and storage of cholesterol in the walls of blood vessels (arteries), thanks to which it may prevent diseases related to the circulatory system.
Magnesium also plays a considerable role in the process of muscle contraction, therefore it influences the activity of the whole muscle system. It also takes part in the proper synthesis of protein, the process of cell division and proper course of energy metabolism. It helps to maintain healthy teeth and bones and general electrolyte balance in the organism.
Vitamin C (ascorbic acid) it is a vitamin soluble in body fluids, can be taken from foods (fruits and vegetables), or as drug derived synthetically. The largest of its resources can be found in broccoli, Brussels sprout, kale, black currant fruit and hawthorn, citrus fruits, tomatoes, Savoy cabbage, potatoes. In fact, intake of vitamin C of the food products does not limit the absorbed quantity. Vitamin C (ascorbic acid) is a potent antioxidant, it is an antitoxic, increasing the immune system due to the elimination of risk of bacterial contamination. Vitamin C prevents rupture of blood vessels, affects the blood cholesterol level. It substantially increases the absorption of iron. Inhibits the growth of cancer cells. Lowers stress levels.
Vitamin C deficiency causes abnormal development of connective tissue, cracking capillaries, abnormal calcification of bone tissue, impaired absorption of iron, scorbutus. With the lack of vitamin C, all kinds of injuries do not heal up properly. Vitamin C deficiency can be caused by smoking; each cigarette is destroying up to 100 mg of vitamin C.
Dosage: The demand is 60-80 mg daily. It does not limit the ability to consume higher doses. Some side effects may occur only with longer taking of synthetic vitamin C.
Ascorbic acid – vitamin C. Its biologically active form is the L-isomer, which negatively rotates the polarised light, so that it is a dextroisomer (laevorotatory vitamin C does not exist). It is a strong antioxidant; it reduces the amounts of free radicals, which reduces oxidative stress, a factor leading to cell apoptosis, which is why it is indicated to be a cause for premature ageing.
It supports the immune system functions and increases body system immunity. It is an essential element of the collagen synthesis path, which is why it positively affects the condition of connective tissue. Hence, it promotes also wound healing and increases the durability of capillary vessel. It is involved in transformations of tyrosine and carnitine as well as of some nutrients, so that it affects metabolism. It can also have an impact on the nervous system functions, as it reduces mental fatigue.
Higher supply of vitamin C is especially recommended in the periods of more intensive body system burden, after infections and in order to accelerate regeneration. The indications for increased supply of the vitamin are also hard physical work or intensive trainings.
Hyaluronic acid (sodium hyaluronate) is a glycosaminoglycan, which do not form covalent bonds with proteins and does not contain sulfate groups. Creates so called proteoglycans aggregates absorbing water and which are responsible for the resistance of cartilage. It is one of the components responsible for the intra-articular fluid viscosity. It takes part in the regeneration of skin tissue. It is synthesized in the body providing a full daily demand. Supplementation applies to athletes exposed to overload of the locomotor system. It is a component of preparations supporting the regeneration of joints and tendons and cosmetics supporting the condition of hair, skin and nails.
Sodium is an important component of the intracellular fluids, and is a regulator of acid-base balance. Along with potassium affects the proper of growth and provides the proper functioning of muscles and nerves. The source of acquisition is table salt (NaCl) and bladderwrack, shellfish, bacon, beef, and of plant beets and carrots. People on salt-free diet should avoid, among others, spicy sauces and smoked meats and sausages.
Sodium deficiency is very rare, at heaving sweating after a long effort (e.g. in the marathon).
Excess sodium increases blood pressure (especially for the elderly), edema and increased thirst. Exceeding the daily dose of 14g a day can cause poisoning.
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