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The supplement contains stimulants which may cause difficulties in falling asleep. Because of that, it is contraindicated to take it in the evening (according the manufacturer’s recommendations, take the product up to 4 hours before bedtime).
The supplement should be used on demand to reduce the development of the body’s tolerance to active ingredients. Since it is high in caffeine, do not take it from other sources.
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Vitamin B3 (vitamin PP, niacin, nicotinic acid, nicotinamide) is niacinamide niacin. It is used in interaction with vitamins B1, B2 and B6 in the synthesis of hormones during lactation. It provides proper functioning of the brain and nervous system. It is helpful in inflammatory conditions of the skin. Required for synthesis of sex hormone, estrogen, testosterone, cortisone, and insulin. It does not lose its properties in the manufacturing and storage. The source of acquiring vitamins PP are both products of animal origin (the lean meat, eggs, fish) and vegetable origin (dates, figs, hazelnuts, plums).
Dosage: 2-12 mg / day for children, 14 mg / day for women, 16 mg / day for men and 17-18 mg / day for pregnant or nursing women.
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Beta-alanine (β-alanine) is a β-amino acid (the same group to which the I-alanine belongs, but with different chemistries). In combination with histidine, it forms β-alanyl-L-histidine (carnosine) - a antioxidant, chelating and buffering compound. Carnosine reduces the level of hydrogen ions in the cell and allows to extend the physical performance and endurance, it affects biological recovery after exercise. Beta-alanine is available in the form of single component and advanced amino-acid supplements, creatine stacks and nitrogen boosters.
Creatine hydrochloride is an advanced form of creatine formed by combining a creatine molecule with hydrochloric acid. Experts estimate that it is 41 times more soluble in water than creatine monohydrate. It also seems to be much more bioavailable for tissues. Increased absorption means that you need smaller doses to obtain the desired results. In addition, excess water retention and gastrointestinal complaints, which often occur while supplementing with other forms of creatine, are no longer a problem. Creatine hydrochloride also does not require a so-called loading phase.
Creatine hydrochloride produces the same effects as other forms of creatine, including the most thoroughly tested creatine mononhydrate. It effectively stimulates ATP resynthesis, may inhibit myostatin activity and supports a healthy nervous system. It has anabolic and anticatabolic properties and helps improve athletic endurance and performance.
In supplementation creatine hydrochloride is available in the form of powder, which is mixed with water, and capsules. It can be often found in complex pre-workout supplements
Dosage: No official guidelines.
The recommended daily dosage is usually 5 g.
Arginine is an exogenous amino acid, it is a component of dietary proteins, not always synthesized in the human body in necessary quantity, so it is necessary to deliver it in the form of synthetics. It takes part in the biosynthesis agmatine, creatine and nitrogen oxides. The use of supplements containing arginine before workout increases the exercise capacity (strength, endurance). Used after considerable effort intensifies the transfer of energy and building compounds and intensifies the process of recovery. Used at bedtime in combination with lysine and ornithine enhances the synthesis of growth hormone. takes part in the intrasystemic synthesis of creatine. Arginine (as a precursor of ornithine) is involved in the urea cycle, increases the flow of blood in the circulatory system, increases sexual potency (in a short time after application). It affects the body's immunity preventing infections, and lowers blood pressure. In supplements – usually as alpha-ketoglutarate.
What is L-Citrulline?
L-Citrulline is an α-amino acid, ornithine derivative. It was isolated for the first time from watermelon and this is how it gained its name, as citrullus in Latin means watermelon. Citrulline takes part in oxygen processes of energy production during effort, thanks to which it is especially attractive for sportsmen of endurance disciplines. It also takes part in urea cycle, also known as the Ornithine cycle, thanks to which it helps to get rid of excessive amounts of ammonia from the organism.
It converts to l-arginine in kidneys and scientific studies suggest that is increases its level even more effectively than in case of sole arginine. Moreover, the increase of arginine level resulting from citrulline supply is longer and more stable. Thanks to this, it contributes to the increase of nitric oxide and widening of blood vessel lumen. This property makes citrulline useful in preventing cardiological incidents. The positive influence on the circulatory system is also used in case of erection disorders, as increased nitric oxide may initiate more effective blood flow to sex organs.
L-Citrulline is contained in the composition of many pre-workout supplements and NO-boosters directed at the improvement of sports abilities of the organism, which may be found in the offer of muscle-zone.pl.
Caffeine (1,3,7-trimethylxanthine, 1-methylotheobromine) is a purine alkaloid occurring in the natural state in plants (Coffea arabica, Camelia sinensis, Paulinia cupana, Ilex paraguariensis), which acts as a natural pesticide, acting toxic to insects. Peculiar smell and taste also deters herbivores. Caffeine in the body inhibits the adenosine receptors in the brain, fighting fatigue and allowing for action activation. It has a beneficial effect on the metabolism of oxygen, which increases the exercise capacity (strength and endurance) and rapid post-workout recovery. In the sports supplementation, caffeine is used as a stimulant nervous system. It has the thermogenic potential and in combination with other substances (e.g. Polyphenols, both occurring in coffee beans, such as cocoa beans, tea leaves and mate) can effectively participate in the reduction of body fat. It is included in many dietary stimulants (creatine stacks, no-boosters, beverages). It is a component of fat burners. It is also in the form of mono-preparation supplements.
Dosage: 100-600 mg per day. Due to the long release of activity should not be used in the evening, before sleep.
Caffeine malate – a combination of caffeine and malic acid which is thus easily absorbed by the body. It is an organic compound which is likely to stimulate human mental activity and has strong energising properties and that is why it is extremely popular among athletes.
Caffeine regulates and maintains healthy blood sugar levels and reduces the incidence of hypoglycaemia. It increases intestinal sugar absorption and can even reduce the demand for glycogen accumulated in muscles, which may contribute to an increase in the body’s endurance.
This compound inhibits the activity of adenosine which calms and relaxes the body. It promotes adrenaline secretion and stimulates the activity of the whole central nervous system.
Caffeine speeds up the release of fats which may also help increase endurance in athletes as a new available source of energy. It contributes to an increase in focus and delays a feeling of fatigue after physical activity.
Citric acid (citric acid, E330) is a ingredient of almost every plant and animal cells, widely used in the food industry as an acidity regulator, emulsifier and stabilizer in order to prevent oxidation and preventing discolouration of the product. In the life processes it takes an active part in the Krebs cycle, a negative phosphofructokinase catalyst, enzyme accelerating the rate of glycolysis. In the sports supplementation used in conjunction with creatine. Preparations available at www.muscle-zone.pl
Choline bitartrate a combination of one molecule of tartaric acid and choline, and in this embodiment is a precursor of acetylcholine (neurotransmitter). The human body is able to intracellular synthesis of choline, using the amino acid and vitamin B12. Because of the possibility of shortages of the above mentioned substances, it is necessary to supplement them with supplementation. Choline is a component of lecithin, which is the building substance of cells conditioning the proper functioning of the nervous system, and sphingomyelin, acting as an insulator of nerve tissue. Bitartrate affects the course of fat metabolism. In the sports supplementation of choline, bitartrate is used in the stimulating supplements,, affecting concentration and programs of weight control (fat reduction).
Dosage: 1-3 grams per day.
L-theanine is an amino acid, not building proteins, occurring naturally in the dried green tea leaves, absorbed from the gastrointestinal tract, overcomes easily blood-brain barrier, affecting the nervous system and the relation between neurotransmitters (e.g.dDopamine, serotonin, gamma-aminobutyric acid), with a relaxing effect and increases the psycho-physical capacity, (concentration, memory, alertness). Recommended for use for people burdened with considerable physical effort, athletes of sport disciplines that require concentration and memory, also for students in the period before exams. Available in the form of mono-preparations and multi-component relaxing and post-workout anti-stress supplements..
Dosage: customarily used in supplementation 50-200mg per day
N-acetyl-L-tyrosine - acetylated form of tyrosine (an endogenous amino acid) improves the solubility and bioavailability of active ingredients. It can be used in lower doses than those taken as free tyrosine. It has a higher availability to the nerve tissue, reduces the feeling of fatigue, improves the exercise capacity psycho (psychostimulant), and, it is a additive to thermogenic effect preparations. It is used in medicine (increases levels of neurotransmitters including dopamine and norepinephrine) and sports dietary supplementation, in pre- and post-workout supplements, as well as fat burners, no-boosters and pre-workout creatine stacks and supplements and energizing beverages.
Dosage: In divided doses ranging from 100-300 mg per day.
Theacrine is a purine alkaloid which occurs naturally in the fruits of cupuaçu (Theobroma grandiflorum) and the leaves of Camellia assamica. It is structurally similar to caffeine but it has also additional ketone and methyl groups. It also energises, enhances focus and reduces drowsiness and fatigue. In contrary to caffeine, it has more lasting effects and rather does not affect blood pressure. Furthermore, it has been observed that the body develops tolerance to theacrine more slowly and that is why there is no need to increase its dosage to obtain the desired results.
Like caffeine, theacrine can bind to adenosine receptors without activating them. Nonetheless, its effects depend on the dosage. Its high doses block adenosine receptors whereas low doses have the opposite effects – they boost adenosine levels in the hippocampus and that is probably why they may reduce negative effects of excessive caffeine intake. In addition, theacrine modulates dopamine receptors. Their activation leads to higher motivation and enhanced cognitive skills. It is also believed to have analgesic and antioxidant effects.
In supplementation, theacrine is treated as a stimulant. It is used to reduce drowsiness and fatigue and boost mental performance. It is often combined with caffeine to enhance and prolong its effects and prevent the harmful consequences of excess caffeine.
Theacrine is most frequently found in pre-workout supplements and fat burners based on stimulants. Single-ingredient preparations with pure theacrine are also available on the market.
Dosage: No official guidelines.
The most common daily dosage is from 50 to 300 mg. Doses below 50 mg will have a relaxing effect and those around 300 mg a stimulating effect.
GABA (gamma amino butyric acid) is an amino acid neurotransmitter fulfilling the role of suppressing, of which precursor is the glutamate (neurotransmitter) excitatory neurotransmitter. Reduces psychophysical tension and cortisol levels, enhances the synthesis of growth hormone having anti-catabolic and regenerating properties. Higher need for GABA by the organism occurs with overtraining, mental exhaustion of the body (stress, depression). Supplementation sports and for physically active people recommended after and during intense exercise. GABA is available in the form of mono-preparation supplement and multicomponent formulations to support the regeneration of the night regenerateion and relaxation of the nervous system.
Dosage: 0,5-3g daily approx. 1 hour before bedtime (single dose, customarily in supplementation).
Yohimbine is a natural component of the indole alkaloid yohimbine, ingredient of bark of yohimbe (Corynanthe yohimbe), a recognized aphrodisiac and increasing potency mean. It stimulates the nervous system by blocking the adrenergic receptors alpha-2. Tree bark of yohimbe is also a source of alkaloids (isoyohimbine, aloyohimbine), which can enhance its performance. With the right dosage, taken with caffeine on an empty stomach and a longer period before taking a meal, it enhances the process of lipolysis due to increased levels of norepinephrine in the body.
In the sports supplementation it helps to reduce body fat (especially in programs of weight control and its composition), taken before physical activity. It comes in the form of mono-preparation supplements, extracts from yohimbe tree bark, synthetics and in supplements with thermogenic effect. Available for purchase at muscle-zone.pl
Dosage: No specific dosage standards. Some sources give optimal dose of 0.2 mg / kg of body weight (usually used at 5-10 mg per day).