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It is worth starting from half a recommended dose, especially in case of people with smaller experience with pre-workouts and those sensitive to stimulants’ effects. It is advisable to take one week breaks in use or take only before most important trainings to maintain high sensitivity to the product’s effects. Evening use may be the cause of sleep problems.
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Vitamin C (ascorbic acid) it is a vitamin soluble in body fluids, can be taken from foods (fruits and vegetables), or as drug derived synthetically. The largest of its resources can be found in broccoli, Brussels sprout, kale, black currant fruit and hawthorn, citrus fruits, tomatoes, Savoy cabbage, potatoes. In fact, intake of vitamin C of the food products does not limit the absorbed quantity. Vitamin C (ascorbic acid) is a potent antioxidant, it is an antitoxic, increasing the immune system due to the elimination of risk of bacterial contamination. Vitamin C prevents rupture of blood vessels, affects the blood cholesterol level. It substantially increases the absorption of iron. Inhibits the growth of cancer cells. Lowers stress levels.
Vitamin C deficiency causes abnormal development of connective tissue, cracking capillaries, abnormal calcification of bone tissue, impaired absorption of iron, scorbutus. With the lack of vitamin C, all kinds of injuries do not heal up properly. Vitamin C deficiency can be caused by smoking; each cigarette is destroying up to 100 mg of vitamin C.
Dosage: The demand is 60-80 mg daily. It does not limit the ability to consume higher doses. Some side effects may occur only with longer taking of synthetic vitamin C.
Ascorbic acid – vitamin C. Its biologically active form is the L-isomer, which negatively rotates the polarised light, so that it is a dextroisomer (laevorotatory vitamin C does not exist). It is a strong antioxidant; it reduces the amounts of free radicals, which reduces oxidative stress, a factor leading to cell apoptosis, which is why it is indicated to be a cause for premature ageing.
It supports the immune system functions and increases body system immunity. It is an essential element of the collagen synthesis path, which is why it positively affects the condition of connective tissue. Hence, it promotes also wound healing and increases the durability of capillary vessel. It is involved in transformations of tyrosine and carnitine as well as of some nutrients, so that it affects metabolism. It can also have an impact on the nervous system functions, as it reduces mental fatigue.
Higher supply of vitamin C is especially recommended in the periods of more intensive body system burden, after infections and in order to accelerate regeneration. The indications for increased supply of the vitamin are also hard physical work or intensive trainings.
Glutamine (L-glutamine) - endogenous amino acid building proteins, glutamic acid amide. In the human body it is responsible for the synthesis of proteins, acid-base balance and removing ammonia from the organism. With the shortage of energy taken from the muscle tissue, glutamine with alanine participate in the process of gluconeogenesis, and participate in the production of glucose substrate. Glutamine has a direct impact on the proper functioning of the digestive system and immune immunity of the organism. Participates in the synthesis of one of the most powerful antioxidant glutathione. It has anti-catabolic potential. It can be found naturally in foods of animal and vegetable origin, protein supplements. Used as mono- or multi-component amino acid supplements, and supplements improving biological recovery after exercise, often in combination with BCAA.
Dosage: 5-20 g per day (portioned during the day, and after training and waking up). The supplementation uses the minimum dose of 2-15g to 1 serving.
Alanine is an endogenous amino acid (i.e. having the ability to synthesize the human body other amino acids and pyruvate), building up protein. It has a key role in the transport of nitrogen between the muscles and the liver (i.e. Cahill cycle). It allows to transform glucose in non-sugar compounds. During prolonged exercise it enhances metabolism. It occurs in products of animal origin (meat, dairy, eggs) and vegetable origins (legumes, peas). It is used in the form of amino acid supplements in pre- and post-workout preparations. It complements the BCAA. Increased use of supplements with alanine is required in athletic training when high strength and endurance is required (e.g. weights lifting athletes marathon runners etc.).
What is L-Citrulline?
L-Citrulline is an α-amino acid, ornithine derivative. It was isolated for the first time from watermelon and this is how it gained its name, as citrullus in Latin means watermelon. Citrulline takes part in oxygen processes of energy production during effort, thanks to which it is especially attractive for sportsmen of endurance disciplines. It also takes part in urea cycle, also known as the Ornithine cycle, thanks to which it helps to get rid of excessive amounts of ammonia from the organism.
It converts to l-arginine in kidneys and scientific studies suggest that is increases its level even more effectively than in case of sole arginine. Moreover, the increase of arginine level resulting from citrulline supply is longer and more stable. Thanks to this, it contributes to the increase of nitric oxide and widening of blood vessel lumen. This property makes citrulline useful in preventing cardiological incidents. The positive influence on the circulatory system is also used in case of erection disorders, as increased nitric oxide may initiate more effective blood flow to sex organs.
L-Citrulline is contained in the composition of many pre-workout supplements and NO-boosters directed at the improvement of sports abilities of the organism, which may be found in the offer of muscle-zone.pl.
Taurine – non-protein amino acid containing sulphur, which is synthesized in the body from methionine and cysteine, present in sufficient amount in human or animal body (in the brain, heart and skeletal), although in some cases must be supplemented. Significantly affects the calcium content in the cells and stabilizes the water and electrolyte balance and maintains acid-base balance. Takes part in the synthesis of bile acids. In the body acts as a neurotransmitter and neuromodulator. It is an insulin-mimetic improving insulin metabolism, responsible for transport of nutrients (such as amino acids, glucose, creatine) to the cells and muscle tissue. These properties determine that it is a valued mono-preparation supplement and valuable addition to creatine and amino acid supplements, recommended for psycho-pchysically active people and athletes and other competitive sportsmen in pre- and post-workout periods.
Dosage: 3 grams per day.
Arginine is an exogenous amino acid, it is a component of dietary proteins, not always synthesized in the human body in necessary quantity, so it is necessary to deliver it in the form of synthetics. It takes part in the biosynthesis agmatine, creatine and nitrogen oxides. The use of supplements containing arginine before workout increases the exercise capacity (strength, endurance). Used after considerable effort intensifies the transfer of energy and building compounds and intensifies the process of recovery. Used at bedtime in combination with lysine and ornithine enhances the synthesis of growth hormone. takes part in the intrasystemic synthesis of creatine. Arginine (as a precursor of ornithine) is involved in the urea cycle, increases the flow of blood in the circulatory system, increases sexual potency (in a short time after application). It affects the body's immunity preventing infections, and lowers blood pressure. In supplements – usually as alpha-ketoglutarate.
Caffeine (1,3,7-trimethylxanthine, 1-methylotheobromine) is a purine alkaloid occurring in the natural state in plants (Coffea arabica, Camelia sinensis, Paulinia cupana, Ilex paraguariensis), which acts as a natural pesticide, acting toxic to insects. Peculiar smell and taste also deters herbivores. Caffeine in the body inhibits the adenosine receptors in the brain, fighting fatigue and allowing for action activation. It has a beneficial effect on the metabolism of oxygen, which increases the exercise capacity (strength and endurance) and rapid post-workout recovery. In the sports supplementation, caffeine is used as a stimulant nervous system. It has the thermogenic potential and in combination with other substances (e.g. Polyphenols, both occurring in coffee beans, such as cocoa beans, tea leaves and mate) can effectively participate in the reduction of body fat. It is included in many dietary stimulants (creatine stacks, no-boosters, beverages). It is a component of fat burners. It is also in the form of mono-preparation supplements.
Dosage: 100-600 mg per day. Due to the long release of activity should not be used in the evening, before sleep.
L-carnitine is a vitamin-like substance, synthesized in the body from amino acids (lysine and methionine) and available in foods of animal origin. It is a component of muscle (including cardiac muscle) and nerve tissue. Involved in the metabolism of fats affecting the transport of long-chain fatty acids into the mitochondria of the cell, facilitating their burning and energy production. It is a potent antioxidant, contributing to the improvement of the aerobic condition and accelerating the recovery after intense exercise. Recommended for use for representatives of endurance sports. In the sports supplementation there are available mono-preparation of carnitine (in liquid form, acetylated [ALC], esterified [see. Propionyl-L-carnitine]) and multicomponent (e.g. in a complex with organic acids - see. L-carnitine tartrate) energetic, weight loss and improving the exercise capacity supplements, to be purchased at www.muscle-zone.pl
Dosage: 1 - 3 g per day in 1 - 3 doses, preferably about 45 - 60 minutes prior to exercise.
Green tea extract is a concentrate that contains biologically active compounds: polyphenols (e.g. catechin, in the form of EGCG - epigallocatechin gallate), having antioxidant properties and a small thermogenic potential, modifies the action of testosterone metabolites, DTH. Green tea extract is an ingredient of many sports supplements containing fat burners, having pro-health and vitaminizing effect; also for those with low physical activity as an antioxidant and slimming supplement. Available either as mono-preparations, ready drinks, and above all as an extract.
Dosage: 200-500 mg per day (depending of the content of other active bio-components).
Theacrine is a purine alkaloid which occurs naturally in the fruits of cupuaçu (Theobroma grandiflorum) and the leaves of Camellia assamica. It is structurally similar to caffeine but it has also additional ketone and methyl groups. It also energises, enhances focus and reduces drowsiness and fatigue. In contrary to caffeine, it has more lasting effects and rather does not affect blood pressure. Furthermore, it has been observed that the body develops tolerance to theacrine more slowly and that is why there is no need to increase its dosage to obtain the desired results.
Like caffeine, theacrine can bind to adenosine receptors without activating them. Nonetheless, its effects depend on the dosage. Its high doses block adenosine receptors whereas low doses have the opposite effects – they boost adenosine levels in the hippocampus and that is probably why they may reduce negative effects of excessive caffeine intake. In addition, theacrine modulates dopamine receptors. Their activation leads to higher motivation and enhanced cognitive skills. It is also believed to have analgesic and antioxidant effects.
In supplementation, theacrine is treated as a stimulant. It is used to reduce drowsiness and fatigue and boost mental performance. It is often combined with caffeine to enhance and prolong its effects and prevent the harmful consequences of excess caffeine.
Theacrine is most frequently found in pre-workout supplements and fat burners based on stimulants. Single-ingredient preparations with pure theacrine are also available on the market.
Dosage: No official guidelines.
The most common daily dosage is from 50 to 300 mg. Doses below 50 mg will have a relaxing effect and those around 300 mg a stimulating effect.
EGCG (epigallocatechin gallate) - a compound occurring naturally in the leaves of green tea and sage nutmeg. Powerful antioxidant resulting in removing free radicals out of your body. It has the thermogenic potential (enhanced when combined with other substances including caffeine, capsaicin, etc.), allowing a faster fat reduction. Affects preventively in the side effects of the glandular hypertrophy (prostate) and male pattern baldness. Recommended for those who are active physically and professionally, for the maintenance of body composition and body aesthetics. It is a component of fat burners, allowing for faster slimming.
Dosage: 50-500 mg per day.
Tyrosine - endogenous amino acid (synthesized within the body), one of the 22 protein amino acids building. It occurs naturally in animal food products (eggs, dairy, meat). If the deficiency, it can be synthesized by hydroxylation of phenylalanine, capable of being converted to tyrosine in the liver. It is a precursor of neurotransmitters: dopamine (the group of catecholamines, participating in the processes occurring in the nervous system, causing muscle coordination and participates in the synthesis of many hormones) and noradrenaline (counteracting stress, stimulating the heart and circulatory system, and increasing glycogenolysis and lipolysis participating in the processes of energy transformations). Tyrosine is a precursor of thyroid hormones responsible for the rate of change in metabolic processes and pigment (melanin). In the supplementation, preparations containing tyrosine are used in programs reducing body fat (weight loss), improve mood and are stimulants.
Dosage: Customarily 500-2000 mg per day.
Cognizin® is a form of citicoline patented by Kyowa Hakko Bio. It is characterized by exceptional stability and purity. It does not contain any allergens and is also suitable for vegetarians. It has been recognized as a safe food additive and is on the GRAS list.
The clinical trials carried out on Cognizin® demonstrated its effectiveness in supporting mental performance, promoting mental functions and increasing the ability to concentrate. The mechanism of its action includes several essential elements. First, citicoline provides essential structural components necessary for the synthesis of nerve cell membranes. Secondly, it contributes to the increase of ATP level and improves energy transformations taking place in the brain. Finally, it supports the production of important neurotransmitters.
On the market, Cognizin® is available in the form of mono-preparations as well as it is found in the composition of various nootropic formulas and in some pre-workout preparations available at www.muscle-zone.pl
Dosage: no standards for unit consumption.
The minimum effective dose indicated in clinical trials is 500 mg, while the maximum is 2000 mg. Higher doses are not recommended.
L-theanine is an amino acid, not building proteins, occurring naturally in the dried green tea leaves, absorbed from the gastrointestinal tract, overcomes easily blood-brain barrier, affecting the nervous system and the relation between neurotransmitters (e.g.dDopamine, serotonin, gamma-aminobutyric acid), with a relaxing effect and increases the psycho-physical capacity, (concentration, memory, alertness). Recommended for use for people burdened with considerable physical effort, athletes of sport disciplines that require concentration and memory, also for students in the period before exams. Available in the form of mono-preparations and multi-component relaxing and post-workout anti-stress supplements..
Dosage: customarily used in supplementation 50-200mg per day
Theobromine (3,7-Dimethylxanthine) is a purine alkaloid, poorly soluble in water, present in cocoa beans, as well as the leaves of yerba mate, tea, coffee, cola and peanuts. It is a diuretic, lowers blood pressure and improves brain function (dilates the blood vessels of the brain). Also expands the blood vessels throughout the circulatory system, preventing atherosclerotic changes. Sometimes it is used in slimming diet. Combined with caffeine and polyphenols becomes thermogenic. In the sports supplementation formulations containing theobromine are used diuretics and fat burners. It is a component of thermogenics, pre-workout creatine stacks, as well as nitrogen boosters.
Astragin is a patented formula, which increases the absorption of amino acids, sugars and vitamins. With insulin sensitivity, it helps to lower blood sugar levels, increasing glycogen reserves up to several dozen percent. It contains natural ingredients, that are extracts of ginseng and astragalus. It is a part of sport diet supplements in the form of pre-workout creatine stacks, amino acid products and so-called "testosterone boosters."
Dosage: 50 mg per day.
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