Agmatine is created in the release of carbon dioxide acids (decarboxylation) in the brain, small intestine, adrenal gland, kidney and liver, and is a metabolite of arginine endogenous enzyme (synthesized by human and animal organisms). The effect on the human body is not fully explored. According to the studies conducted so far show the features of andrenergic imidazole receptors. The proper availability in the body increases the activity and may affect the lipolysis process and the synthesis of nitric oxide. Not occurring in the natural, but in the combination with other oxides of nitrogen (arginine and citrulline), it has become one of the basic components of keratin stacks, NO boosters and pre-workout products, widely used in sports supplementation.