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Creatine Orotate Ethyl Ester, made from binding of molecules of creatine and orotic acid in a molecule as a result of the esterification process. Orotic acid (vitamin B13) belongs to the group of water soluble vitamins, is involved in the metabolism of folic acid (vitamin M) and vitamin B12. It occurs in plant products. It cures multiple sclerosis. It affects the production of energy through the increase of uridine monophosphate (UMP) and the level of 5-phosphoribosyl-1-pyrophosphate (PRPP), increasing storage of glycogen in the muscles. Creatine (β-methylguanidoacetic acid) is an endogenous substance, synthesized from the acids present in liver and kidney (L-arginine, L-glycine and L-methionine) and the consumption of meat. Its operation provides keeping a level of Adenosine triphosphate (ATP), which is an energy carrier, increases the hydration of muscle cells and stores glycogen. In the sports supplementation ,creatine is stored in the muscles, which improves energy management, exercise capacity and quick recovery and muscle growth. It has the ergogenic, anabolic and anti-catabolic potential. A combination of these components with the systematic application increases the functional capacity (strength and endurance), increase lean body mass and acceleration of the wellness of the body after exercise. Because of anabolism insulin, increasing creatine transport into muscle cells ,it is recommended to combine it with supplements that increase insulin sensitivity (and insulin-mimetics). Creatine Orotate Ethyl Ester, is used among athletes involved in strength and endurance sport, is available as mono-preparation supplements (powders, capsules) or as a base component of the creatine stacks at www.muscle-zone.pl.
Dosage: The dose used should be chosen by a doctor or dietician, depending on the type of exercise, length of cycle (cycles of short duration, constant supplementation), and the weight applying:
- The supplementation cycles of 4 - 12 weeks, 5 - 10 g / 24h (in single or divided doses up to 3 servings / 24h)
- Continuous supplementation from 0.03 g - 0.05 g / kg of body weight

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