Octopamine (beta-4 dioxyphenethylamine) - the natural form found in fruit, bitter orange (Citrus aurantium). Citrus auratuim extract (extract of bitter orange) is widely used in the process of weight reduction, active people, as well as people having the so-called. sedentary lifestyle. It is a source of synephrine and octopamine, which in combination with caffeine and polyphenols, contained in green tea, affect lipolysis, releasing fatty acids of adipocytes, by causing increased energy expenditure, burning them in the sources of vital energy cells (mitochondria). Contraindication is the use by patients with hypertension and neurological disorders. It is popular after the banning of ephedrine by WADA (dangerous for the body) .In supplementation, octopamine (extract from bitter oranges) is part of the weight loss supplements (i.e. Thermogenic), pre-workout creatine stack and nitrogen boosters.