Ornithine belongs to endogenous non-protein amino acids, it is produced by transformation of the amino acid arginine and glutamic acid. It is an intermediate in a metabolic cycle urea synthesis from ammonia and carbon dioxide. The degradation of amino acids in the liver making the first removes nitrogen (alpha amino groups are transferred to alpha-ketoglutarate) and leads to the formation of glutamate, transformed into the form of ammonium ions. It is necessary to neutralize the highly toxic ammonia, which is carried out by aspartate, creating argininosuccinate. A further phase of change is the formation of arginine and fumarate. Then the cycle is repeated. In the transition process, ornithine is the starting material for the enzyme that catalyses a particular stage of the urea synthesis. It is also an acceptor for the synthesis of citrulline. Ornithine, through the synthesis of polyamines, has a regenerating effect on the liver.
Ornithine is available as mono-preparation (often included with the other ingredients of supporting liver function) and multi-component supplements containing ornithine aspartate. Indispensable in sports supplementation in no-boosters (pre-workout products) as it stores the arginine, it slows down its expenditure and allows for more effective use in the synthesis of nitric oxide. Available in the full range at: www.muscle-zone.pl
Dosage: There are no specific standards for daily consumption. 200 - 1500 mg / 24h, commonly used in supplementation.