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Excessive intake of L-arginine may cause gastrointestinal problems which lead to diarrhoea. The maximum recommended dosage is 10 mg. This is backed by scientific studies which say that the biovability of L-arginine after a dose of 6 g is 68% (rounded to 69%) whereas after a dose of 10 g is just 20%.
Do not take L-arginine together with antihypertensives, as this may drastically reduce your blood pressure. It is contraindicated to take it with medications improving blood flow because this may lead to vertigo. Do not take arginine during viral infections because it may stimulate the replication of viruses.
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Arginine alpha-ketoglutarate (AAKG) is a salt glutaric acid and arginine. The presence of these compounds results in intensification of the operation of each of them. Arginine alpha-ketoglutarate improves the bioavailability by stimulating the decomposition to CO2 and H2O, which means that it becomes a precursor in the synthesis of nitric oxide. It has anti-catabolic properties enhancing anabolism. Enhances the functioning of the insulin hormone, insulin-mimetics IGF-1) and somatotropin growth hormone.
AAKG is part of the pre-workout supplements (improving muscle blood flow and increasing the exercise capacity (strength and endurance)), as well as improves the recovery process after training. Most often used to increase the synthesis of nitric oxide (supplements pre- and post-workout), increasing muscle blood flow and regeneration. Particularly valued by the representatives of power sports, power and strength sports and strength athletics. Used very often in the rehabilitation of sports injuries.
Arginine is an exogenous amino acid, it is a component of dietary proteins, not always synthesized in the human body in necessary quantity, so it is necessary to deliver it in the form of synthetics. It takes part in the biosynthesis agmatine, creatine and nitrogen oxides. The use of supplements containing arginine before workout increases the exercise capacity (strength, endurance). Used after considerable effort intensifies the transfer of energy and building compounds and intensifies the process of recovery. Used at bedtime in combination with lysine and ornithine enhances the synthesis of growth hormone. takes part in the intrasystemic synthesis of creatine. Arginine (as a precursor of ornithine) is involved in the urea cycle, increases the flow of blood in the circulatory system, increases sexual potency (in a short time after application). It affects the body's immunity preventing infections, and lowers blood pressure. In supplements – usually as alpha-ketoglutarate.
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