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|Servings: 60 caps.|
To assess the tolerance to supplement, should start with 1 capsule in the morning for the first 2-3 days. If no adverse reactions occur, the dose may be increased to 1 capsule in the morning and 1 capsule in the afternoon. We do not recommend exceeding the dose of 1 capsule per serving and 2 capsules within 24 hours. For best results, the preparation should be supplemented in combination with a proper diet and training. To avoid insomnia and over-stimulation late in the evening, do not take the preparation within 5 hours before bedtime.
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Caffeine (1,3,7-trimethylxanthine, 1-methylotheobromine) is a purine alkaloid occurring in the natural state in plants (Coffea arabica, Camelia sinensis, Paulinia cupana, Ilex paraguariensis), which acts as a natural pesticide, acting toxic to insects. Peculiar smell and taste also deters herbivores. Caffeine in the body inhibits the adenosine receptors in the brain, fighting fatigue and allowing for action activation. It has a beneficial effect on the metabolism of oxygen, which increases the exercise capacity (strength and endurance) and rapid post-workout recovery. In the sports supplementation, caffeine is used as a stimulant nervous system. It has the thermogenic potential and in combination with other substances (e.g. Polyphenols, both occurring in coffee beans, such as cocoa beans, tea leaves and mate) can effectively participate in the reduction of body fat. It is included in many dietary stimulants (creatine stacks, no-boosters, beverages). It is a component of fat burners. It is also in the form of mono-preparation supplements.
Dosage: 100-600 mg per day. Due to the long release of activity should not be used in the evening, before sleep.
Higenamine affects the production of nitric acid. Nitric acid affects the release of the hormones and adrenaline. It is also certain that the product accelerates regeneration of the body and also increases the amount of blood flow, and thus the amount of nutrients delivered to the muscles is much greater.
Choline bitartrate a combination of one molecule of tartaric acid and choline, and in this embodiment is a precursor of acetylcholine (neurotransmitter). The human body is able to intracellular synthesis of choline, using the amino acid and vitamin B12. Because of the possibility of shortages of the above mentioned substances, it is necessary to supplement them with supplementation. Choline is a component of lecithin, which is the building substance of cells conditioning the proper functioning of the nervous system, and sphingomyelin, acting as an insulator of nerve tissue. Bitartrate affects the course of fat metabolism. In the sports supplementation of choline, bitartrate is used in the stimulating supplements,, affecting concentration and programs of weight control (fat reduction).
Dosage: 1-3 grams per day.
Rutaecarpine is an alkaloid of plant origin - Evodia Rutaecarpa, a source of evodiamine. (evodiamine, plant alkaloid [family Rutacea] thermogenic and a stimulant effect. In supplementation in programs to improve body composition and aesthetics, it is used for its thermogenic potential, allowing for fast fat burning). It affects the metabolic activity of liver enzymes. Administered with other ingredients rutaecarpine increases their concentration in the plasma, while vasodilation. It affects the operation of nitric oxide (NO) in the organism . In the sports supplementation used in the form of creatine stacks, no-boosters and fat burners, as a substance that enhances the activity of the other ingredients, available at www.muscle-zone.pl
It is also in the form of mono-preparation, however, not available on the Polish market
Dosage: the lack of strict standards of daily consumption
Evodiamine is an alkaloid with thermogenic and stimulating effect, allowing for faster burning of lipids, with an action similar to capsaicin. Source of evodiamine is plant of the family Rutacea. In the sports supplementation, its thermogenic potential is used in the combination with caffeine and green tea, as part of enhancing body fat reduction, improveing the body composition and aesthetics. It is also used by people with low physical activity in the weight loss process. It is a component of stimulating supplements (boosters and pre-workout creatine stacks)
The coffee bean extract, a source of polyphenols. Coffee seeds has chemical composition similar to green tea and grape seed. They neutralize free radicals and intensify burning processes and inhibit the formation of fat in the body, in addition to caffeine contains chlorogenic acid, an antioxidant that is slowing down the absorption of glucose from the gastrointestinal tract. It affects the fat reduction, intensifying the activity in combination with caffeine and EGCG. It is a component of many dietary supplements and slimming preparations improving health prevention.
Chlorogenic acid is a polyphenol found in many plants, including in particular the green fruit of the coffee plant, artichoke, nettle and prunes. Different than it is in the case of green coffee beans, roasted coffee beans contain a much smaller amount of the compound, since it is degraded during thermal treatment. This acid is antibacterial, antioxidant, and also a positive effect on glucose metabolism. Reduces the absorption of sugar from the gastrointestinal tract and improves insulin sensitivity. These properties of chlorogenic acid indicates that the compound is used in weight loss, which is also confirmed by a number of clinical trials carried out, showing its efficacy in reducing body mass. It should, however, be emphasized, that accurate analyses also showed that after the withdrawal of chlorogenic acid, they body mass may increase again.
Dosage: The recommended daily dose of chlorogenic acid is 800 mg.
Theacrine is a purine alkaloid which occurs naturally in the fruits of cupuaçu (Theobroma grandiflorum) and the leaves of Camellia assamica. It is structurally similar to caffeine but it has also additional ketone and methyl groups. It also energises, enhances focus and reduces drowsiness and fatigue. In contrary to caffeine, it has more lasting effects and rather does not affect blood pressure. Furthermore, it has been observed that the body develops tolerance to theacrine more slowly and that is why there is no need to increase its dosage to obtain the desired results.
Like caffeine, theacrine can bind to adenosine receptors without activating them. Nonetheless, its effects depend on the dosage. Its high doses block adenosine receptors whereas low doses have the opposite effects – they boost adenosine levels in the hippocampus and that is probably why they may reduce negative effects of excessive caffeine intake. In addition, theacrine modulates dopamine receptors. Their activation leads to higher motivation and enhanced cognitive skills. It is also believed to have analgesic and antioxidant effects.
In supplementation, theacrine is treated as a stimulant. It is used to reduce drowsiness and fatigue and boost mental performance. It is often combined with caffeine to enhance and prolong its effects and prevent the harmful consequences of excess caffeine.
Theacrine is most frequently found in pre-workout supplements and fat burners based on stimulants. Single-ingredient preparations with pure theacrine are also available on the market.
Dosage: No official guidelines.
The most common daily dosage is from 50 to 300 mg. Doses below 50 mg will have a relaxing effect and those around 300 mg a stimulating effect.
L-carnitine tartrate is formed from the combination of L-carnitine tartrate (organic acid) in a single molecule, increasing the interaction (synergism) of each of the substances used. L-carnitine is supplied to the body from the outside through animal food (mutton, beef, venison) or a combination of amino acids (lysine and methionine). It participates in the transport of long-chain fatty acids into the mitochondria of the cell where they are burned. Tartrate reduces the deposition of fatty acids in the cells, thereby enhancing the effects of L-carnitine. It is recommended in endurance sports supplementation, as a dietary supplement for people on a slimming diet and to supplement the shortage of l-carnitine of people not consuming meat products (vegans).
Olive leaf extract is produced from the leaves of the olive (Olea Europea) is the source of oleuropein, coumarin derivative, belonging to secoiridoids. It effects: increases thermogenesis, leading to a reduction in body fat, increases the immune system, minimizing the risk of developing heart disease and cancer. It is also supporting the fight against free radicals.
Olive leaf extract is a component of weight loss supplements (including thermogenic), antioxidants sets, used in the composition of pre-workout supplements in sports supplementation.
Grains of Paradise (Aframomum melegueta) - Melegueta pepper, a perennial plant in the ginger family, Zingiberaceae. It is used as seasoning, although its properties used in supplementation are much more interesting.
When it comes to biological activity Aframomum melegueta demonstrates considerable similarity to ginger. It is used as therapy in the treatment of eating disorders, reduces digestive discomfort and supports the functionality of intestines.
Aframomum melegueta is also a frequent ingredients of weight loss supplements, due to its ability to increase insulin sensitivity. In this way, it supports proper metabolism of carbohydrates, the disorders of which are a common reason for problems with weight loss. Some sources also say that Aframomum melegueta increases metabolic rate, promoting basic daily energy expenditure of the organism.
This plant is also used as aphrodisiac. According to some sources it may increase the level of testosterone, although current studies do not confirm this scope of effectiveness of Aframomum melegueta.
6-paradol is a bioactive chemical compound found in some plants of the ginger family. It is found in particularly large amounts in Aframomum melegueta, commonly known as the Grains of Paradise. In studies on animal models, 6-paradol has been shown to positively affect the lipid profile and sugar metabolism – by lowering serum glucose and reducing cholesterol. It also helps to reduce body mass. Such results were obtained even in animals that were fed with an unhealthy, high-fat diet.
Researchers identified several essential mechanisms of 6-paradol activity. They proved that it increases the use of glucose through a separate, non-insulin dependent pathway. In addition, it inhibits the synthesis of lipids in adipocytes. It also has a thermogenic effect – it is able to stimulate the expression of brown adipose tissue that is responsible for the generation of heat.
In supplementation, 6-paradol is mainly used as a support for the process of reducing body fat. It can be found in many slimming preparations. There are also Aframomum melegueta extracts available on the market, standardized for the content of 6-paradol.
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