- Natural fat-breaking aid
- Positive effects on the cardiovascular system
- Anti-inflammatory and analgesic properties
- Stimulation of the pancreas to secrete insulin
- Increased secretion of digestive enzymes
- Increase in muscle anabolism
- Regulation of blood glucose levels
- Lowering eye pressure
- Optimization of lipid profile
- Stimulation of testosterone synthesis
- Mitigation of allergic reactions
- Inhibition of fat synthesis
- Reduction of cortisol levels
- Enhancement of lipolysis processes
- Stimulation of thermogenesis
- Increasing fertility
Swanson Coleus Forskohlii is a natural dietary supplement containing powdered Indian nettle root(Coleus forskohlii), which contains a significant amount of forskolin, which supports fat reduction and has a positive effect on cardiovascular function.
Indian nettle (Plectranthus barbatus syn. Coleus forskohlii) is a plant that has been used for centuries in Ayurveda and traditional Indian medicine. Indian nettle's greatest popularity has come from its fat-reduction-stimulating properties. In addition, it is also used for cardiovascular problems, gastrointestinal ailments, obesity, respiratory diseases, hypertension, glaucoma and psoriasis. The main active substance present in Indian nettle is forskolin, a compound from the diterpene group. The largest amounts of forskolin are found in the root of the plant.
The mechanism of action of forskolin is the stimulation of adenylate cyclase due to direct action on this enzyme. Adenylate cyclase catalyzes the conversion of ATP into cAMP (cyclic AMP, cyclic adenosine-3′,5′-monophosphate). Cyclic AMP is a universal secondary information transmitter that participates in many biochemical reactions and affects the activity of numerous genes. It activates protein kinase A, which phosphorylates proteins. Phosphorylation of proteins determines their physiological function.
An increase in cAMP levels causes activation of hormone-dependent cholesterol lipase (HSL), which catalyzes hydrolysis reactions of acylglycerols, cholesterol esters and other steroids. This causes, among other things, the release of free fatty acids from acylglycerols, which are the body's energy reservoir. Inhibition of lipid synthesis in adipocytes (yellow adipose tissue cells) and intensification of lipolysis processes results in a reduction of adipose tissue.
cAMP is involved not only in lipolysis, but also participates in glycogen breakdown, gluconeogenesis, ketogenesis, insulin release by the pancreas and many other biochemical processes.
Forskolin can increase free testosterone levels in men, as indicated by a 2006 experimental study. The increase in testosterone increases the body's anabolic potential, stimulates the formation of muscle tissue and the degradation of body fat. It also has a positive effect on the body's endurance and muscle strength. Forskolin can therefore facilitate the building of muscle tissue and body shape.
Forskolin is used for conditions underlying low levels of intracellular cAMP. Such conditions include psoriasis, hypertension and obesity, among others. Forskolin also exhibits anti-inflammatory properties, reduces platelet aggregation, minimizing the risk of blood clots, and lowers elevated blood pressure due to its vascular smooth muscle relaxant effect. Thus, it shows positive effects on the cardiovascular system.
In conclusion, Swansol Coleus Forskohlii is a dietary supplement that supports the process of fat reduction in a natural, safe way. It is a very good support in body building, facilitating the gain of lean body mass. It is especially recommended for people who train, aiming to develop an athletic physique, for overweight and obese people, as well as to increase the body's performance and fitness.
