- Standardized Ginkgo biloba extract
- Improves peripheral and cerebral circulation
- Counteracts cellular hypoxia
- Has a beneficial effect on the cardiovascular system
- Increases levels of neurotransmitters
- Improves memory and cognitive function
- Recommended for white-collar workers
- Counted as a "brain booster"
Now Foods Ginkgo Biloba is a dietary supplement containing an extract (EGb 761) ofginkgo biloba leaves (Ginkgo biloba extract) standardized to contain a minimum of 24% ginkoglycoflavonoids and 6% terpenolactones.
Ginkgo biloba(Ginkgo biloba) - the world's oldest tree with numerous health-promoting and medicinal properties; it has been used in traditional Chinese medicine for more than 5,000 years, also known as ginkgo biloba. The medicinal raw material is mainly leaves, from which extracts or extracts are prepared. The main biologically active substances of ginkgo leaves are flavonoids (isoramnetin, kemferol, quercetin, biflavones, oligomeric proanthocyanidins) and terpenoids (ginkolides A, B, C, J, M and bilobalide)
Proanthocyanidins (condensed tannins) have anti-inflammatory, superoxide free radical inhibitory, vascular protective, blood glucose lowering, antiviral, antibacterial, anti-allergic, anti-cancerogenic and anti-proliferative properties. They account for roughly 7% of standardized extracts.
Ginkgolides (diterpene lactones) exhibit a specific chemical structure previously unknown in the plant world. They reduce the activation and aggregation (clumping) of platelets, improve circulation, and are antagonists of platelet-activating factor (PAF) - an unfavorable factor that damages internal organs and generates cardiovascular diseases. In addition, ginkgolide B acts as a free radical scavenger.
Bilobalide (trilactone sesquiterpene) is a unique compound found only in ginkgo. In animal studies, it reduces cytotoxic cerebral edema (artificially induced), reduces the volume of cortical necrosis and brain damage resulting from stroke ischemia. It improves blood flow and enhances oxygen and glucose utilization by cells in the central nervous system (CNS). In addition, it is a monoamine oxidase (MAO-A and MAO-B) inhibitor, increasing amine neurotransmitter levels. Studies have also shown the anti-stress and anti-anxiety effects of bilobalide.
Flavonoids exhibit antioxidant activity by quenching free radicals, chelating pro-oxidant heavy metal ions, increasing superoxide dismutase (SOD) activity and increasing glutathione levels.
Properties of Ginkgo Biloba extract: (based on basic in vitro/in vivo and clinical studies)
--> Cardiovascular system:
- Strengthens the walls of arterial and venous blood vessels
- Inhibits capillary permeability
- Dilates constricted blood vessels in a physiological manner (PAF antagonism)
- Prevents vascular calcification
- Inhibits platelet aggregation and reduces blood viscosity
- Improves rheological parameters of blood
- Improves tissue and organ perfusion
- Increases the release of vasodilator factor EDRF in endothelial cells
- Inhibits free radical formation and reduces membrane lipid peroxidation
- Antagonizes homocysteine-induced oxidative stress and NF-κB factor activation.
- Reduces myocardial contractile dysfunction caused by ischemia
Properties of Ginkgo Biloba extract: (based on basic in vitro/in vivo and clinical studies)
--> Nervous system:
- Protects brain tissue from hypoxia and ischemia
- Improves peripheral and cerebral circulation
- Improves memory and facilitates concentration
- Energizes mentally, adds vitality
- Normalizes age-dependent deficiencies of neurotransmitters
- Has a beneficial effect on synaptic remodeling
- Increases concentrations of dopamine, serotonin and norepinephrine
- Increases the integrity of the blood/brain barrier
- Inhibits the formation of β-amyloid aggregates
- Decreases the activity of the enzyme caspase-3 (prevents neuronal apoptosis)
- Increases the number of 5-HT1A receptors in the cerebral cortex
- Reversibly inhibits monoamine oxidase (MAO A and B)
- Has a beneficial effect on the treatment of Alzheimer's disease
- Improves brain function and quality of well-being in healthy individuals aged 50-65 years
- Shows therapeutic effects in the treatment of dementia conditions
It should be taken as a correction that not all clinical studies have confirmed the above effects of Ginkgo biloba extract, and some even contradict specific specifications. Ginkgo biloba's health and therapeutic properties are still controversial and contradictory, so no official recommendations have been made so far for strictly medical use.
Notes for use
Due to its strong anticoagulant effect, it should not be combined with the use of heparin, warfarin, aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs).
In conclusion, Now Foods Ginkgo Biloba is a dietary supplement that can be used to improve memory and cognitive function, as well as to strengthen the circulatory system and counteract its dysfunction. It is recommended for students, white-collar workers, and prophylactically for the elderly.
