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According to clinical research related to anti-diabetes action, the beneficial influence of Gymnema sylvestre may be felt at the dose of 200-400 mg of the extract. It is recommended to use the preparation for max. 20 months.
It is best to take the preparation with a meal or 5-10 minutes before, as when taken on an empty stomach, it may be the source of discomfort and stomach-intestinal disorders.
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GS4 PLUS® is a patented Gymnema sylvestre leaf extract, standardized for 75% of gymnemic acid. The trademark rights are held by Sabinsa Corporation – a recognized manufacturer and supplier of herbal extracts and specialty chemicals for the pharmaceutical, food and cosmetics industries. GS4 PLUS® has been the subject of numerous clinical trials with the participation of healthy people and diabetics, who confirmed the safety of its use even in a long-term run.
Studies proved that GS4 PLUS® has the ability to lower blood sugar levels. It uses the action of gymnemic acid, which increases the activity of enzymes responsible for the metabolism of sugars, and at the same time limits the expression of enzymes that condition gluconeogenesis. The compound may also increase the release of insulin and improve the regeneration of pancreatic islets. In addition, through the not yet identified mechanism, it temporarily blocks sensing sweet taste, and thus naturally reduces appetite for sweet foods. Less known, but equally well-documented, are the anti-inflammatory and cardioprotective properties of GS4 PLUS®.
In supplementation, GS4 PLUS® is available in the form of tablets and capsules. It is also part of many preparations aimed at optimizing the use of carbohydrates and reducing appetite.
Dosage: no standards for unit consumption.
In clinical trials, doses of 400-500 mg per day were used.
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