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Take capsules with or shortly after a meal, as that is when glucose and lipid spikes occur.
Do not take too much berberine at once, as it can result in cramping, diarrhoea, an upset stomach; it should always be taken throughout the day. Because berberine easily reacts with other substances, consult a doctor if you take any medication.
Although berberine demonstrates phenomenal effect both in people who try to lose weight and those with glucose-insulin balance problems, it is advised to use the preparation with caution during the period of building muscle mass by healthy and physically active people. Studies show that provoking constant activity of AMPK may decrease the pace of muscle mass growth. Bearing this in mind, in the periods of building muscle mass, it is rather recommended to limit the application of the supplement only to high-carbohydrate meals.
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