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Along with vitamin D, the proper supply of calcium is necessary for optimal health of skeletal system. Taking the formulation simultaneously with productsthat are rich in calcium or diet supplements containing calcium will increase the intake of this element.
For better bioaccessibility, it is best to take the formulation with a mealcontainingfat.
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Fish oil is a source of long chain saturated fatty acids of the Omega-3 (EPA - eicosapentaenoic acid; DHA - docosahexaenoic acid), which are part of cell membranes and the precursor of eicosanoids, and an activator. When consuming acids Omega 3, it must be balanced with the Omega 6 (using in the range of from 1: 6 to 1: 1). Fats contained in fish oil help to reduce body fat, affect the oxygenation of the body, and the operation of systems: circulatory, respiratory, nervous system and the musculoskeletal system. Available in the form of mono-preparation supplement or as an ingredient of supplements in the category of "health and beauty".
Omega-3 (n-3) group of unsaturated fatty acids: short-chain (linolenic acid, belongs to the EFAs [essential fatty acids]) and long-chain (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]). The number 3 indicates That the last double bond in the carbon chain is the third from the end of carbon. Acids from the group of Omega-3 are essential components of cell membranes, they are biological precursors and activators of eicosanoids. EFAs quite abundantly supplied in food, and it can be supplied with food. EPA and DHA (oils, fats marine fish) are Supplied by foods of sea origin (sea fish and seafood). They are developed also in the human body as a result of processes of denaturation and elongation of alpha-linolenic acid , but in an amount insufficient for the full needs of the organism. Therefore,they should be supplied from the outside. With the use of so-called. western diet, supplementation of fatty acids Omega 3 is more desirable (than Omega 6).
Supplementation of fatty acids of Omega 3 is recommended for people who are physically active in order to supplement and to prevent deficiencies in body as well as due to their impact on the body composition and aerobic capacity, and tissue regeneration. In addition, it regulates the systems: circulatory (including heart), nervous, respiratory and locomotor. Formulations containing EPA and DHA are a complement to an effort diet, regardless of the degree of training and exercising.
Dietary fatty acids Omega 3, in principle, are produced in the form of capsules in combination with vitamin E as an antioxidant, available for purchase at: www.muscle-zone.pl
Dosage usually we recommended supplements in sports: depending on the supply of diet and intake of Omega 6 it is 1 - 5 g of EPA and DHA / 24 h.
EPA (eicosapentaenoic acid) – what is it?
EPA (eicosapentaenoic acid) is a long-chain, polyunsaturated omega-3 fatty acid. The chain of the fatty acid consists of 20 carbon molecules, and the first bound out of five double bounds is located at the third carbon from the omega end, which is characteristic for omega-3 acids. It is present in large quantities in fish oils, where it is accompanied by docosahexaenoic acid (DHA).
EPA is a precursor to prostaglandins and other eicosanoids, which contributes to the reduction in inflammations. It is involved in inhibition of platelets aggregation. It contributes also to the reduction in triglycerides level in blood. EPA block the activity of an enzyme, phospholipase A2, present on cell membranes, which under the influence of stressors can release polyunsaturated fatty acid (from the group of eicosanoids) into the glycerol skeleton. To some extent, EPA can be also converted into 22-carbon DHA. The both acids have positive impact on the condition of the nervous system and cardiovascular health.
Eicosapentaenoic acid contained in dietary supplements with omega-3, which are available in the offer of muscle-zone.pl
DHA (docosahexaenoic acid) - acid of omega-3 family, unsaturated fatty acids with the last double bond in the chain located on the third carbon atom from the end. Synthesized in the human body to eicosapentaenoic acid, or retrieved from foods of marine origin (fish, particularly salmon). In the medicine it is indicated for the treatment of depression, Alzheimer's ADHD. There has been its positive impact on the insulin metabolism noted as well as on endocrine and cardiovascular systems. When used in appropriate doses, it has a beneficial effect on the composition and appearance of the body. In the the supplementation it is part of formulas containing fish oil, which fill in the gaps of unsaturated fatty acids Omega 3, recommended for people with different physical activity.
Dosage: 200-2000 mg per day
Vitamin D belongs to fat soluble vitamins, occurs in three forms: calciferol (vitamin D1) ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3), it is formed under the action of sunlight for at least 15 minutes per day. In the absence of sunlight it should be administered in the diet in the form of fish oil (Vitamin A + D3) and fish oils. It is responsible for the absorption of calcium and phosphorus. It is the building substance of bone tissue particularly necessary during pregnancy, childhood, and for athletes. It is a component of dietary supplements and nutrients among competetive athletes. Deficiency of vitamin D causes children growth inhibition, and rickets.
For adults - deficiency causes osteomalacia.
Excess of vitamin D causes headaches, alopecia, nausea, drowsiness, blurred vision, pain in the long bones, the deposition of calcium deposits.
Dosage: 400 IU units during the day.
Cholecalciferol, or vitamin D3, is an organic chemical that belongs to the family of D vitamins. It is naturally found in fatty fish, fish oil, egg yolks, milk and dairy products. It is also synthesized in the human body. It is formed from 7-dehydrocholesterol present in the keratinocytes of the spinous and the basal layers of the epidermis, and a pre-requisite for initiating this process is the action of 290-315 nm wavelength UVB radiation on the skin.
Cholecalciferol is a biologically inactive compound. In the body, it undergoes enzymatic hydroxylation – first in the liver, with the participation of 25-hydroxylase, when calcidiol is formed and secondly in the kidneys, where under the influence of 1-α-hydroxylase, calcidiol is converted into the final active form – calcitriol.
The most important role of vitamin D3 in the body is the regulation of calcium-phosphate metabolism, which directly affects normal skeletal mineralization. In addition, it is involved in cell proliferation and differentiation, insulin secretion, as well as in some functions of the nervous, endocrine and immune systems.
Cholecalciferol is the most popular form of vitamin D used in dietary supplements. Studies show that supplementation with vitamin D in this form most effectively and rapidly raises the level of 25 (OH) D3 – a metabolite that is a marker of the level of vitamin D in the body.
Dosage: according to RDI standards for individual age groups.
Vitamin K exists in the triad of vitamins: menaquinone (vitamin. K1), menadione (vitamin. K2) and menadione (vitamin. K3), soluble in fat. It is produced by bacteria in the human colon. Natural sources of vitamin. K are: eggs, kale, cauliflower, cabbage, meat, milk, lettuce, spinach, fish oil and liver. The synthetic form is administered to newborns, to reduce the sterility of the gastrointestinal tract. Used as a antihaemorrhagic, due to its participation in the process of prothrombin. Increases antibacterial and antifungal immunity. Prevents abundant bleeding during menstruation of women.
Vitamin K deficiency causes external bleeding and ecchymosis on skin, decreased prothrombin synthesis in the liver (especially while taking antibiotics and sulfanilamide).
What is menaquinone-7?
Menaquinone-7 is a term used for long-chain form of vitamin K2, having seven isoprene residues in the side chain. Contrary to another popular form MK-4, it is not synthesized in tissues, however, it may be produced in the intestines by means of the conversion from vitamin K1 by intestinal bacteria.
It exhibits especially positive influence on the health of the circulatory system, especially by lowering the risk of atherosclerosis and heart attacks. It owes this effect mainly to osteocalcin, activated by vitamin K2. This hormone is responsible among others for the transport of calcium to bones, which counteracts its storage in soft tissues, decreasing at the same time the probability of blood vessel calcification and the creation of atherosclerotic plaques. K2 MK-7 also contributes to protecting the nervous system, securing neurons from excitotoxicity induced by excessive activity of glutamate and reducing the consequences of excessively low level of glutathione.
Vitamin K2 in the form of menaquinone-7 is a very popular additive to supplements with vitamin D3, due to the synergy of effects and reducing potential negative effects of applying higher doses of cholecalciferol.
Menaquinone-7 may be found both in monopreparations and complex supplements in the offer of muscle-zone.pl.
Vitamin E (tocopherol) is a fat soluble. Due to its antioxidant action, it is a protection of other vitamins (e.g. Vitamins A). Protects the body against free radicals, strengthens the walls of blood vessels and its capacity, causing their dilation and dissolution of blood clots. With the reduction of coagulation, it is used as an antiatherogenic medicine, it allows for the proper course of pregnancy. In cooperation with selenium it slows the ageing process of cells, strengthening connective tissue. In the food it is present in whole-grain bread, sprout and grains, vegetable oils (soybean, sunflower), soya beans and sunflower seeds, vegetable fat and hen egg yolks. Also it is used in sports medicine in the form of nutrients and supplements.
Vitamin E deficiency reduces building of red blood cells, results in changes in muscle and disorders of pregnancies.
Dosage: for children, 0.5 mg / 1 kg of weight; for adults 10-30 mg per day.
D-alpha-tocopherol – a natural form of vitamin E which is indicated as the most optimum for supplementation. It helps correct effectively deficiencies of this compound which is extremely crucial for the human body.
Vitamin E is a very important bioactive substance found in many tissues and required for normal functioning of the body. Its deficiencies may be manifested by impaired cognitive abilities and vision, muscle weakness and infertility. It is involved in erythropoiesis and that is why its low intake may lead to anaemia.
In addition, vitamin E has an important role as an antioxidant in the human body. It has the ability to reduce the amount of free radicals, thereby decreasing negative oxidative stress.
During supplementation with d-alpha-tocopherol, we should remember that it belongs to fat-soluble compounds, along with vitamin A, D and K. Because of that, supplements with vitamin E should be taken with a fat-containing meal.
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