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As a standard, doses of 100-200 mg per day are used in supplementation. Higher doses are not recommended, although there are reports of 300-mg doses used in patients with deep depression. Nevertheless, note that since 5-HTP crosses the blood-brain barrier and easily increases serotonin levels, it is not recommended to consumer higher doses without specialist supervision. Also remember that the preparation is intended for temporary use rather than long-term, regular supplementation.
The supplement must not be combined with any antidepressant, especially SSRIs and MAO inhibitors.
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5-HTP (5-hydroxytryptophan) is a metabolite of essential amino acid, tryptophan, involved in the synthesis of serotonin which is a neurotransmitter and a hormone responsible for the quality of sleep (melatonin). Used in medicine as an adjuvant, to a small extent supporting the treatment of depression and insomnia. Due to the presence of melatonin at the same time it is improving the quality of sleep and improving the regeneration process.
5-HTP is a component of supplements supporting the production of growth hormone and it is a part of some fat reducers (reducing appetite).
Dosage: Doses commonly used in supplements, depending on the purpose: 100-500 mg daily in divided doses, including approx. 50-150 mg before bedtime.
Extract Griffonia Simplicifolia is the source derivative of tryptophan (5-HTP), an important neurotransmitter involved in the synthesis of serotonin, and indirectly affects the production of melatonin (the hormone responsible for sleep). It is used to treat depression and inactivity. In the sports supplementation it is used as a neurotransmitter responsible for the quality of sleep and improving the regenerative processes, moreover, it is a component of supplements which enhances the secretion of growth hormone and fat burners.
Dosage: In terms of 5-HTP from several dozen to several hundred mg per day.
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