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B vitamins exert a stimulatory effect on some people, so to avoid problems with falling asleep, they should be taken in the first half of the day.
During supplementation, after taking the preparation, you may experience such effects as short-term redness on the face (caused by a high dose of niacin) or bright yellow color of the urine (caused by a high dose of riboflavin) may appear. This is perfectly normal and does not pose a health risk.
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Vitamin C (ascorbic acid) it is a vitamin soluble in body fluids, can be taken from foods (fruits and vegetables), or as drug derived synthetically. The largest of its resources can be found in broccoli, Brussels sprout, kale, black currant fruit and hawthorn, citrus fruits, tomatoes, Savoy cabbage, potatoes. In fact, intake of vitamin C of the food products does not limit the absorbed quantity. Vitamin C (ascorbic acid) is a potent antioxidant, it is an antitoxic, increasing the immune system due to the elimination of risk of bacterial contamination. Vitamin C prevents rupture of blood vessels, affects the blood cholesterol level. It substantially increases the absorption of iron. Inhibits the growth of cancer cells. Lowers stress levels.
Vitamin C deficiency causes abnormal development of connective tissue, cracking capillaries, abnormal calcification of bone tissue, impaired absorption of iron, scorbutus. With the lack of vitamin C, all kinds of injuries do not heal up properly. Vitamin C deficiency can be caused by smoking; each cigarette is destroying up to 100 mg of vitamin C.
Dosage: The demand is 60-80 mg daily. It does not limit the ability to consume higher doses. Some side effects may occur only with longer taking of synthetic vitamin C.
Ascorbic acid – vitamin C. Its biologically active form is the L-isomer, which negatively rotates the polarised light, so that it is a dextroisomer (laevorotatory vitamin C does not exist). It is a strong antioxidant; it reduces the amounts of free radicals, which reduces oxidative stress, a factor leading to cell apoptosis, which is why it is indicated to be a cause for premature ageing.
It supports the immune system functions and increases body system immunity. It is an essential element of the collagen synthesis path, which is why it positively affects the condition of connective tissue. Hence, it promotes also wound healing and increases the durability of capillary vessel. It is involved in transformations of tyrosine and carnitine as well as of some nutrients, so that it affects metabolism. It can also have an impact on the nervous system functions, as it reduces mental fatigue.
Higher supply of vitamin C is especially recommended in the periods of more intensive body system burden, after infections and in order to accelerate regeneration. The indications for increased supply of the vitamin are also hard physical work or intensive trainings.
Vitamin B1 (thiamin, vitamin B) improves mental alertness and strengthens the nervous system ensuring the proper functioning of the brain. It improves cardiac and muscular system. It is suportive in the treatment of shingles. Involved in the metabolism of carbohydrates and fats. Natural source of vitamin B1 are brown bread, yeast, eggs, raw vegetables, meat, milk, legumes, cheese.
Vitamin B1 deficiency hinders the processes of decomposition of sugars (catabolism), causes a loss of appetite and disorders in the functioning of the digestive tract, can cause polyneuritis and disease beriberi.
Dosage: Recommended daily intake is 1-2 mg.
Thiamine hydrochloride - a highly bioavailable form of thiamine, also called vitamin B1. Due to an important role that it plays in carbohydrate metabolism, its increased supply is recommended to people with excessively high concentration of sugar in blood. It facilitates their processing in the organism and supports the activities that aim at restoring optimal glycemia. An important role in the metabolism of nutrients is also played by an integral component of carboxylase coenzyme - thiamine pyrophosphate.
Some source suggest the effectiveness of thiamine in relation to the health of the cardiovascular system, apart from decreasing glucose level in blood, it is also reflected in optimization of blood pressure. Although this aspect of effectiveness of vitamin B1 requires further research, it is another argument demonstrating special needs of taking care of proper thiamine supply by people from the risk group of the circulatory system diseases.
Among people who are especially prone to vitamin B1 deficiencies there are also people fighting with excess weight and frequently drinking alcohol.
Vitamin B2 (riboflavin) is soluble in liquids, is involved in the metabolism of proteins, fats and carbohydrates. Required for growth of the organism. Takes part in the production of erythrocytes (red blood cells). It is located in natural foods, such as yeast, meat (especially liver, kidney, heart), milk, fish and green leafy vegetables.
A deficiency of vitamin B2 inhibits the growth, diseases of the mouth, loss and greasy hair, seborrhea and stratification of nails. Increases skin roughness and susceptibility to acne and oily skin.
Dosage: 1-2 mg per day.
Vitamin B3 (vitamin PP, niacin, nicotinic acid, nicotinamide) is niacinamide niacin. It is used in interaction with vitamins B1, B2 and B6 in the synthesis of hormones during lactation. It provides proper functioning of the brain and nervous system. It is helpful in inflammatory conditions of the skin. Required for synthesis of sex hormone, estrogen, testosterone, cortisone, and insulin. It does not lose its properties in the manufacturing and storage. The source of acquiring vitamins PP are both products of animal origin (the lean meat, eggs, fish) and vegetable origin (dates, figs, hazelnuts, plums).
Dosage: 2-12 mg / day for children, 14 mg / day for women, 16 mg / day for men and 17-18 mg / day for pregnant or nursing women.
Nicotinic acid amide – also known as nicotinamide, belongs to a group of compounds referred to as vitamin B3, along with nicotinic acid and inositol hexanicotinate. It exerts its main biological activity as a precursor to two key coenzymes for efficient energy metabolism of the body: nicotinamide adenine dinucletodide and nicotinamide adenine dinucleotide phosphate. They are responsible for carrying hydrogen and electrons in the respiratory chain and thus facilitate efficient energy production by the human body.
Nicotinamide supplementation is recommended for active persons not only because of its ability to promote the body’s energy efficiency. It has also a beneficial impact on mind, increases tolerance to stressors and may reduce symptoms of depression. It is pointed out that niacin supplementation correlates positively with sleep quality.
Unlike nicotinic acid, nicotinamide does not show the ability to produce a “flush effect”, namely redness in the face caused by taking large doses of niacin. It has been also shown to influence partly cardiovascular function.
Nicotinamide is also indicated to influence beneficially the absorption of other B vitamins and vitamin D. This compound should be taken with caution by diabetics because it can increase the body’s demand for insulin.
Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
Pyridoxal 5-phosphate (P-5-P) - the form of vitamin B6, called coenzymatic, considered the best assimilable form of this vitamin by the human organism. This is related to direct metabolic activity of pyridoxal-5-phosphate in the human organism. It does not have to be subjected to biochemical transformations in the organism in order to be able to enter metabolic pathways as a biologically active ingredient.
Vitamin B6 is an incredibly important factor regulating the work of many processes in the organism due to its role in the organism as a coenzyme, essential for the activation of many important enzymes. Thanks to this, it regulates metabolism at many levels and its proper supply is conducive to maintaining homeostasis of the organism.
Another aspect of effectiveness of vitamin B6 is its influence on the normalization of emotional states. It is conducive to relaxation, facilitates falling asleep and falling in a deep, the most valuable sleep. Special influence on P5P on the psyche is proven in women before menstruation, as it demonstrates considerable ability to reduce the symptoms of the pre-menstrual syndrome.
Supplementation with vitamin B6 also demonstrates positive influence on the functions of the nervous system. It is conducive to the nourishment of neuronal tissues and optimizes the secretion of neurotransmitters, thanks to which it promotes nervous transmission and demonstrates neuroprotective properties. It was proven that vitamin B6 may decrease the risk of developing Parkinson’s disease.
Some sources also suggest the ability of pyridoxal 5-phosphate to reduce the risk of cancer. This effectiveness is noted especially in relation to breast cancer.
Folic acid - also known as vitamin B9, is a synthetic form of naturally occurring folates. It needs to be transformed to folates in order to be biologically active also in the human organism. Therefore, its supplementation is recommended to people who do not have problems with methylation processes.
The majority of people associate folic acid with the period of pregnancy. It is definitely a justified association. Proper supply of vitamin B9 conditions correct development of the fetus and prevents disorders of neural tube defects in a baby.
Supplementation with folic acid also demonstrates positive influence on the functions of the nervous system of adults. Some sources say that it is conducive to maintaining beneficial emotional states. Moreover, folic acid takes part in the process of erythropoiesis, thanks to which it enables efficient production of red cells.
Supplementation with folic acid should be also considered by men who deal with low sperm quality. It was proven that complementing the level of vitamin B9 is conducive to increasing reproductive abilities of men.
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Vitamin B12 (cobalamin, cyanocobalamin) is a vitamin soluble in liquids. Participates in the production of red blood cells and is essential in the absorption of iron by the body. It calming effect, a positive effect on concentration and memory. Intensifies its action in cooperation with folic acid (vitamin M). Usually occurs in animal products, fish and dairy products. It contains trace elements.
Vitamin B12 deficiency can lead to pernicious anaemia, general and immunity weakness, inhibiting of growth and damage to the myelin sheath of nerves.
What is methylcobalamin?
Methylcobalamin is a biologically active form of vitamin B12. It is one of the two forms of this vitamin that may be used as cofactors in various reactions. It differs from popular cyanocobalamin in the presence of methyl group instead of cyanide, thanks to which it releases the organism from the need of neutralizing this harmful factor.
The methyl group from methylcobalamin may be transferred to homocysteine, thanks to which it comes back in the form of methionine in order to be further converted to SAMe, which is the main donor of methyl groups in our organism. These methyl groups may be then used in the processes of creatine production, in neurotransmitter metabolism and as DNA methylation, thanks to which we achieve proper energy level, better well-being and generally better condition of the organism. B12 is a coenzyme for three enzymes: isomerase, methyltransferase and dehalogenase.
Apart from the influence on the nervous system, the supply of vitamin B12 is also very important for the proper synthesis of red cells as well as hemoglobin and anemia prevention.
Methylcobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
Biotin (vitamin H, co-enzyme R) is in a group of B vitamins, due to the presence of sulphur compounds it is involved in the synthesis of ascorbic acid (vitamin C). Also synthesized in the intestines. It enhances the production of hormones and regulates cholesterol levels. It reduces muscle pain. It prevents hair loss and graying of hair. It soothes the skin inflammations. No toxic effects. Often combined with other B group vitamins and vitamin A. The natural sources of biotin are: whole grain bread, yeast, eggs (yolk), milk, brown rice and cheese.
Daily demand: 100-300 mg per day
Calcium panthonenate – a salt of pantothenic acid and calcium used to raise the intake of this first substance, belonging to a group of compounds called vitamin B5. It is active in many biochemical processes in the human body as an extremely important factor for maintaining homeostasis.
Adequate intake of pantothenic acid helps maintain healthy metabolism of nutrients and obtain easily energy from them. Deficiencies of this compound may be manifested by chronic fatigue and lack of strength, especially in physically active persons.
What is more, pantothenic acid is present in the synthesis pathway of many vital hormones. Because of that, its sufficient supply is critical to hormonal balance. Testosterone is one of the hormones that are affected by pantothenic acid intake. Because of that, its deficiencies may have a negative effect on sexual function.
Pantothenic acid is also indicated to have a cardioprotective effect. It helps maintain normal cardiac function and reduces the risk of atherosclerosis by optimising the lipid profile.
Vitamin B5 (calcium pantothenate, pantothenic acid, pantotenol) is part of a complex of B vitamins affects the development of the central nervous system, is the building substance of cells. In the body synthesized by the intestinal bacteria. It occurs in animal products (meat, kidneys, liver) and plants (wheat germ, wheat bran, nuts, grains, green vegetables). Prevents fatigue and excessive stress, accelerates the healing of cuts and wounds, acts as a stimulant for the side effects of the use of antibiotics. Deficiency causes skin changes, and difficulty in blood clotting.
Choline belongs to the soluble in liquids group of B vitamins. It is an organic nitrogen base containing lecithin, and acetylcholine. Together with inositol is involved in the metabolism of fats and cholesterol metabolism, preventing its accumulation on the walls of arteries and deposits in the gallbladder. With the penetration of the brain, contained lecithin improves its action and improves memory. Used in the treatment of age-related diseases (Alzheimer's). It occurs in plant foods: yeast, wheat germ, lecithin, green leafy vegetables and egg yolks.
Choline bitartrate a combination of one molecule of tartaric acid and choline, and in this embodiment is a precursor of acetylcholine (neurotransmitter). The human body is able to intracellular synthesis of choline, using the amino acid and vitamin B12. Because of the possibility of shortages of the above mentioned substances, it is necessary to supplement them with supplementation. Choline is a component of lecithin, which is the building substance of cells conditioning the proper functioning of the nervous system, and sphingomyelin, acting as an insulator of nerve tissue. Bitartrate affects the course of fat metabolism. In the sports supplementation of choline, bitartrate is used in the stimulating supplements,, affecting concentration and programs of weight control (fat reduction).
Dosage: 1-3 grams per day.
Inositol is an organic compound from the group of B vitamins soluble in fluids, present in the natural or synthetic form, synthesized in plants, such as brewer's yeast, beans, grapefruit, cabbage, sprout of wheat, melons and animal (liver). Along with choline is included in the lecithin. It affects the cell nutrition of the central nervous system (brain) by reducing the level of LDL (bad cholesterol), this makes it applicable in treatment of Alzheimer's disease and atherosclerosis. It has a calming effect. There has been a beneficial effect of inositol on the skin and hair reported.
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