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It is advisable to take the preparation during the main meal. The supplement is based only on natural ingredients, which makes it very safe even during prolonged use.
The supplement is recommended during periods of liver burdening, resulting from either a poor diet or an excess of stimulants. It will also be a good choice for athletes after cycles with doping agents.
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Extract from milk thistle (Silybum marianum) a plant of the Asteraceae family, of which a source of active substances are fruit, providing silymarin (silibilina, silydianina, silichrystyna in the ratio of 2: 1: 1), an antioxidant, natural protection of liver cells, affecting positively the level of glutathione, anti-inflammatory properties (slow release of prostaglandins, and histamine). It affects the blood lipid profile by lowering levels of LDL cholesterol. It is used in medical prophylaxis and treatments (food poisoning, liver disease and in case of high calorie diet). Available in the form of mono-preparation supplements and multicomponent supplements supporting the work of the digestive system and the liver in the "health."category. Preparations available at www.muscle-zone.pl
Dosage: Dose converted into silymarin, from 200 to 400 mg / 24h
L-aspartate L-ornithine (salt of the amino acids L-ornithine and L-aspartic acid), which is involved in the detoxification of ammonia and affecting regeneration of liver cells. L-aspartic acid is involved directly or synthetics in assisting in the physiological processes: energy conversion, synthesis of purines and urea enhances the synthesis of nitric oxide. L-ornithine, endogenous non-protein amino acid which is a precursor of arginine. Mediates in the metabolic cycle of urea synthesis from ammonia and nitrogen excretion. It is a citrulline acceptor. Synthesizes polyamines regenerating the liver. Part of the preparations for health, used in supplementation in the form of no-boosters. Available at the www.muscle-zone.pl
Dosage: varied from a few dozen mg to a few g / 24h
Choline belongs to the soluble in liquids group of B vitamins. It is an organic nitrogen base containing lecithin, and acetylcholine. Together with inositol is involved in the metabolism of fats and cholesterol metabolism, preventing its accumulation on the walls of arteries and deposits in the gallbladder. With the penetration of the brain, contained lecithin improves its action and improves memory. Used in the treatment of age-related diseases (Alzheimer's). It occurs in plant foods: yeast, wheat germ, lecithin, green leafy vegetables and egg yolks.
Artichoke extract - an extract of Mediterranean perennial, which is a rich source of active compounds, such as chlorogenic acid (eg. cynarine), sesquiterpenes (eg. cynaropicrin), flavonoids and glycosides. Artichoke extract is widely used in medicine: a shielding action for liver, stabilizing cell membranes, is antioxidant, inhibiting oxidation of LDL cholesterol (the so-called bad cholesterol). In the etching process, not only protects the gastrointestinal tract itself, but by increasing the secretion of digestive juices, beneficial effect on the assimilation of nutrients. It has a soothing effect on the digestive system. It has a slight potential diuretic.
Extract of artichoke is an extract used in health-enhancing supplements, supporting digestion, protecting the liver and lowering LDL cholesterol. It is often combined with other plant extracts, and aspartate-I-ornithine.
Dosage: 600-1000 mg per day.
Cysteine belongs to the group of essential amino acids, synthesized by the body, involved in detoxification of the body. The combination of L-cysteine with glutamine and glycine is involved in the synthesis of glutathione (a powerful antioxidant) and the proteins, enzymes and co-enzymes. Present in the protein product, in smaller amounts in corn and peanuts. The source of the acquisition are also concentrates and whey protein isolates, and preparations containing mixtures of amino acids. Not in the form mono-preparations. It is a component of detoxification, supporting the work of the liver supplements and in supplements improving the cosmetics of the body, usually in the form of L-cystine (two connected cysteine particles) or in the form of NAC.
Dosage: the usual supplementation: 50-500 mg per day.
Exogenous methionine is an amino acid containing sulphur in its composition. It provides multi metabolism, with the indispensable help of vitamin B6. Participates in the synthesis of phospholipids (e.g. Lecithin), carnitine responsible for transport in the body of long-chain fatty acids, burned in the mitochondria cells (organelles in cells with a separate kernel), along with cystine forms cysteine. It is in the body antioxidant function. Natural source of acquisition of methionine are high-protein foods of animal origin (eggs, meat, fish), vegetable (sesame seeds, grain products). Available in all protein and carbohydrate protein and amino acid supplements such EAA and contain so-called all-day amino acids, supporting the liver preparations and cosmetics supporting the growth and condition of hair, skin and nails.
Dandelion (Taraxacxum officinale) is a common weed occurring in the temperate climate zone. The raw materials of medicinal are root (Radix Taraxaci) and flower (Flos Taraxaci), rich in active ingredients (phytosterols, insulin, pectin, organic acids, choline, mineral salts - the root, flavonoids, carotenoids, triterpenes, reducing sugars, essential oil - in flowers ). It has diuretic properties, promoting processes of reducing body fat, removing excess fluid from the body and the overall impact on the operation of the digestive system. Sensitized to insulin. Used as a component in supplements to reduce body, fat burners and diuretics. With long-term use, it should be supplemented with electrolytes. In the sports supplementation known as Dandelion Root.
Berberine – an isoquinoline alkaloid naturally appearing i.a. in common barberry (Berberis vulgaris). Berberine is a substance which has been known for hundreds years, which is attributed strong anti-inflammatory, antioxidant, anticancer, antibacterial (especially when it comes to Gram-positive bacteria), antiviral, antifungal and anti-protozoan properties. This compound regulates proper functioning of the cardiovascular system.
Numerous clinical studies on the activity of berberine confirm its hypoglycemic properties - it decreases the increased glucose level in blood and normalizes lipid profile - influences decreasing the concentration of LDL, total cholesterol and triacylglycerols and increases the level of HDL in blood, i.a. thanks to supporting liver work. There are some studies confirming positive influence of berberine on alleviating the symptoms of polycystic ovary syndrome (PCOS) and acne. This substance also positively influences cognitive functions.
Berberine may decrease the production of glucose in the liver and influence the improvement of tissue sensitivity to insulin. For this reason, supplements with berberine are reccomended as support in the therapy of insulin-resistance, diabetes, metabolic syndrome, excess weight and obesity. Berberine is also the component of dietary supplements supporting weight loss.
With the simultaneous application of medicines, be careful, as berberine may interact with some pharmacologically active substances.
N-acetyl-L-cysteine (NAC), acetylated form of cysteine, one of the 22 amino acids building proteins, of wide use in medicine and sports supplements. Neutralizes the effects of paracetamol overdose, it is protecting on the liver, influences on the synthesis of glutathione, and the nervous system (effect on NMDA receptors). It increases the body's immunity to inflammation (especially of the upper respiratory tract). Available in the form of medicines and dietary supplements in sports pharmacies and www.muscle-zone.pl
Dosage: the lack of standards unit consumption. Doses as customarily used in supplementation.
Turmeric (Curcuma longa) is a plant of Asian, with the ginger family with a strong odour, contains curcumin, used as a dye (orange-yellow) for the food, e.g. rice, a spicy and acrid taste, soluble in fat and alcohols (water insoluble) . The raw material is the rhizome of turmeric, also containing an essential oil. It is used for prophylactic treatment because of its anti-inflammatory, antioxidant, antipyretic and cholagogic properties. Significantly increases thermogenesis, enhancing fat reduction. Its effects in the treatment of cancer (certain destroys cancer cells) have been proven. In the supplement it is available as a component of fat burners and supplements which improve the work of cartilage and joint tissue.
Glutathione (GSH), also known as y-glutamylcysteine glycine, is one of the most common low-molecular thiol compounds. It is found both in prokaryotic and eukaryotic organisms.
A reduced form of glutathione is the most important element of the antioxidant system which is responsible for the protection of cells against harmful effects of reactive oxygen species. Apart from its direct antioxidant effect, glutathione has also the ability to regenerate other antioxidants, such as vitamin C and E. It is also involved in the repair of protein molecules, lipids and nucleic acids whose damage was caused by peroxidation reactions. It participates in xenobiotic metabolism.
Maintaining healthy intracellular glutathione levels is extremely important for creating an optimum environment for our immune function and detoxification and antioxidant processes. What is more, glutathione has a major role in the circulatory and digestive system (helps fight intestinal inflammation and ulcers).
Glutathione supplementation has therefore a wide range of uses. Formulas with this ingredient are recommended especially to individuals who want to promote general health. They can also bring great benefits for athletes in whom intense physical activity leads to overproduction of free radicals.
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