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The recommended dosage can be extended by any situations related to snacking between the main meals rich in carbohydrate, provided that the unplanned snack also contained carbohydrates. Depending on their amount, the dose can be reduced accordingly.
Tip for physically active people – a great option is to take a dose of the preparation accompanied by a portion of carbohydrates consumed immediately after physical exercise.
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Chromium (chemical element from transition group of the chromium, chemically active) is actively involved in the metabolism of fats and carbohydrates. It comes in the easily assimilable organic form and inorganic. Along with insulin, as a component of the glucose tolerance factor (GTF), is used in insulin-dependent diabetes treatment, insulin involved in the metabolism of glucose in t proteins transport. Activator of enzymes involved in the metabolism of fats and cholesterol. Available in animal origin products (liver, veal, chicken, turkey meat, oysters) and plant-origin (bananas, broccoli, cereal, wheat germ, spinach). Supplements containing chromium are recommended for fat loss (also thermogenic), and improving the functioning of the body. The sports supplementation used chromium in the form of mono-preparations or in the form of vitamin-mineral minerals supplements.
Chromium deficiency results in impaired glucose, reducing the insulin sensitivity. It causes a decrease in immunity and endurance of the body. It may be a cause of coronary heart disease. Sometimes it causes neurological disorders.
Dosage: A varied diet prevents from the deficiency of chromium in the body.
Dosage: The recommended dose of 50-150 mg per day.
Berberine – an isoquinoline alkaloid naturally appearing i.a. in common barberry (Berberis vulgaris). Berberine is a substance which has been known for hundreds years, which is attributed strong anti-inflammatory, antioxidant, anticancer, antibacterial (especially when it comes to Gram-positive bacteria), antiviral, antifungal and anti-protozoan properties. This compound regulates proper functioning of the cardiovascular system.
Numerous clinical studies on the activity of berberine confirm its hypoglycemic properties - it decreases the increased glucose level in blood and normalizes lipid profile - influences decreasing the concentration of LDL, total cholesterol and triacylglycerols and increases the level of HDL in blood, i.a. thanks to supporting liver work. There are some studies confirming positive influence of berberine on alleviating the symptoms of polycystic ovary syndrome (PCOS) and acne. This substance also positively influences cognitive functions.
Berberine may decrease the production of glucose in the liver and influence the improvement of tissue sensitivity to insulin. For this reason, supplements with berberine are reccomended as support in the therapy of insulin-resistance, diabetes, metabolic syndrome, excess weight and obesity. Berberine is also the component of dietary supplements supporting weight loss.
With the simultaneous application of medicines, be careful, as berberine may interact with some pharmacologically active substances.
Bitter melon (Momordica charantia), also known as balsam-pear or bitter squash, is a kind of a plant in the family Cucurbitaceae, coming from tropical terrains. The plant has been used for millenniums in Ayurveda. The material here are fruits, characterized with bitter taste, containing i.a. amino acids, phenolic acid, rutin and polypeptide-p - a protein imitating the activity of insulin, called plant insulin.
The activity of bitter melon consists in regulating and supporting the maintenance of the proper glucose concentration in blood by means of a few mechanisms. There are ca. 120 scientific studies confirming hypoglycemic activity of this plant. Moreover, extracts from this plant support digestion and liver work.
Bitter melon has normalizing influence on the level of total cholesterol, LDL fraction and triacylglycerols in blood, thanks to which it supports weight loss, maintaining proper body mass and may constitute a valuable element of prophylaxis of cardiovascular system diseases. Preparations based on bitter melon demonstrate antioxidant potential, supporting reduction of inflammations and thanks to immunomodulating properties, they boost the organism’s immunity.
Traditionally, this plant was used to support the treatment of diabetes, in gastric ailments, as an anthelminthic agent, in the therapy of cough and other ailments of the respiratory system, infections, ulcers and skin diseases, i.a. psoriasis.
GS4 PLUS® is a patented Gymnema sylvestre leaf extract, standardized for 75% of gymnemic acid. The trademark rights are held by Sabinsa Corporation – a recognized manufacturer and supplier of herbal extracts and specialty chemicals for the pharmaceutical, food and cosmetics industries. GS4 PLUS® has been the subject of numerous clinical trials with the participation of healthy people and diabetics, who confirmed the safety of its use even in a long-term run.
Studies proved that GS4 PLUS® has the ability to lower blood sugar levels. It uses the action of gymnemic acid, which increases the activity of enzymes responsible for the metabolism of sugars, and at the same time limits the expression of enzymes that condition gluconeogenesis. The compound may also increase the release of insulin and improve the regeneration of pancreatic islets. In addition, through the not yet identified mechanism, it temporarily blocks sensing sweet taste, and thus naturally reduces appetite for sweet foods. Less known, but equally well-documented, are the anti-inflammatory and cardioprotective properties of GS4 PLUS®.
In supplementation, GS4 PLUS® is available in the form of tablets and capsules. It is also part of many preparations aimed at optimizing the use of carbohydrates and reducing appetite.
Dosage: no standards for unit consumption.
In clinical trials, doses of 400-500 mg per day were used.