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I recommend to take half of the serving suggested by the manufacturer and then increase it gradually up to one full serving if necessary. Take preferably the lowest effective serving.
Due to the content of stimulants, the formula should not be used with other stimulants. Do not take it in the late afternoon and evening to avoid sleep problems.
Ribose is a simple sugar produced within the organism, included in the nucleic acid [RNA (ribonucleic acid) and DNA (deoxyribonucleic)], containing information on genetic factors affecting growth and development and normal functioning of cells. The appropriate amount of ribose adopted in the supplementation guarantees the resoring and proper energy conversion, both ATP and ADP and increasing aerobic capacity, improves the functioning of the heart and muscles. It is recommended especially the use of preparations containing ribose for people at high physical exertion and those whose body does not produce sufficient amounts of ribose. Supplements available at www.muscle-zone.pl
Beta-alanine (β-alanine) is a β-amino acid (the same group to which the I-alanine belongs, but with different chemistries). In combination with histidine, it forms β-alanyl-L-histidine (carnosine) - a antioxidant, chelating and buffering compound. Carnosine reduces the level of hydrogen ions in the cell and allows to extend the physical performance and endurance, it affects biological recovery after exercise. Beta-alanine is available in the form of single component and advanced amino-acid supplements, creatine stacks and nitrogen boosters.
Arginine is an exogenous amino acid, it is a component of dietary proteins, not always synthesized in the human body in necessary quantity, so it is necessary to deliver it in the form of synthetics. It takes part in the biosynthesis agmatine, creatine and nitrogen oxides. The use of supplements containing arginine before workout increases the exercise capacity (strength, endurance). Used after considerable effort intensifies the transfer of energy and building compounds and intensifies the process of recovery. Used at bedtime in combination with lysine and ornithine enhances the synthesis of growth hormone. takes part in the intrasystemic synthesis of creatine. Arginine (as a precursor of ornithine) is involved in the urea cycle, increases the flow of blood in the circulatory system, increases sexual potency (in a short time after application). It affects the body's immunity preventing infections, and lowers blood pressure. In supplements – usually as alpha-ketoglutarate.
What is L-Citrulline?
L-Citrulline is an α-amino acid, ornithine derivative. It was isolated for the first time from watermelon and this is how it gained its name, as citrullus in Latin means watermelon. Citrulline takes part in oxygen processes of energy production during effort, thanks to which it is especially attractive for sportsmen of endurance disciplines. It also takes part in urea cycle, also known as the Ornithine cycle, thanks to which it helps to get rid of excessive amounts of ammonia from the organism.
It converts to l-arginine in kidneys and scientific studies suggest that is increases its level even more effectively than in case of sole arginine. Moreover, the increase of arginine level resulting from citrulline supply is longer and more stable. Thanks to this, it contributes to the increase of nitric oxide and widening of blood vessel lumen. This property makes citrulline useful in preventing cardiological incidents. The positive influence on the circulatory system is also used in case of erection disorders, as increased nitric oxide may initiate more effective blood flow to sex organs.
L-Citrulline is contained in the composition of many pre-workout supplements and NO-boosters directed at the improvement of sports abilities of the organism, which may be found in the offer of muscle-zone.pl.
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Alpha-ketoglutarate (ionized Alpha-ketoglutarate acid, ketone derivative of glutaric acid). Involved in the metabolism of amino acids, oxidation, and transport of the nitrogen in the body. It accelerates the synthesis of components of food (anti-catabolism). In sports supplementation it is used in combination with arginine, glutamine and BCAA. As it is of excreting a toxic ammonia from the body - it is antitoxin. It is a part of sports pre- and post-training supplements, and anti-catabolic supplements and amino acid complexes.
Creatine (β-methylguanidoacetic acid) is an endogenous substance, synthesized from the acids present in liver and kidney (L-arginine, L-glycine and L-methionine) and consumption of meat. Its action ensures an adenosine triphosphate (ATP) level, which is an energy carrier, increases the hydration of cells and muscle glycogen stores. In the sports supplementation creatine is stored in the muscles, which improves energy management, exercise capacity and quick recovery and muscle growth. It has the ergogenic, anabolic and anti-catabolic potential.
Creatine is one of the high-performance substances used in competitive sports, with a reputation confirmed by scientific research. In the form of mono-preparation supplements such as creatine ester, creatine malate, creatine monohydrate, and the multi-component supplements (both various forms of creatine, as well as other substances, precursors of nitric oxide, the BCAA type amino acids). Supplements containing creatine available for purchase at www.muscle-zone.pl
Dosage: depending on the form of preparation, the type of exercise and weight, normally one of the following models of creatine dosage is used:
- cyclic supplementation: 5 - 10g per day in 1 - 3 portions a day, 2 - 5 g per dose. Cycle time approx. 4 - 12 weeks
- cyclic supplementation with saturated phase: first 5 - 7 days 20 - 30g per day on Day 4 - 6 doses 4 - 6g per serving, then the maintenance phase 2 - 10g per day in divided doses. Cycle time approx. 4 - 8 weeks
- constant supplementation: 0.03 - 0.05 g per kg body weight for an extended period of time.
Creatine monohydrate is a popular and cheapest form of creatine used in sports supplementation in Poland. This is a molecule, in which are bound: creatine molecule with a molecule of water. It has a high bioavailability and tissue velocity saturation. Supports the exercise capacity (strength and endurance), accelerates muscle growth and regeneration after training exercise. Transport of creatine into the muscle cells is supported by the insulin hormone. For better effect of saturation of the tissues, a diet increasing the content of insulin in the body is indicated (carbohydrate and high protein diet) and supporting nutrients and supplements (Dietary carbohydrate and carbohydrate-protein, insulin ALA, d-pinitol or taurine). Creatine monohydrate is present in the form of mono-preparation supplements (capsules, powders, tablets) and multicomponent supplements (i.e. as a component of creatine stacks).
Dosage: depending on the form of supplement, the type of exercise and weight, normally are used one of the following models of creatine supplementation:
- cyclic supplementation : 5-10g per day in 1-3 portions during the day, 3-5g per dose. The length of the cycle for 4-8 weeks.
- cyclic supplementation with saturated phase: the first 5-7 days after 20-30g daily in 4-6 doses of 4-6g per serving, then the maintenance phase 2-10g per day in divided doses. The length of the cycle 4-8 weeks
- constant supplementation: 0,03-0,05g per kg of body weight for an extended period of time.
Buffered creatine monohydrate is a special formula combines creatine monohydrate with the so-called "Buffer", which is a chemical compound that allows to obtain the proper pH of the solution, the aim of its development was to eliminate the conversion of creatine to form creatinine. The formula is modelled on the patented Kre-ALKALYN formula. Buffered creatine monohydrate improves the exercise capacity (strength and endurance), accelerates the growth of lean body mass, and provides extensive wellness after exercise. It is available as both a mono-preparation supplement in a form of capsules (rarely as powder), as a basis or supplementation of creatine stacks.
Dosage: in professional sport recommended 2.5-7.5 grams per day, depending on the intensity of the workout.
Creatine citrate is formed from the combination of creatine molecules and three molecules of citric acid in one molecule. It is a substance soluble in body fluids, more soluble than creatine monohydrate. Ionized citric acid (citrate) is involved in energy conversion, by acting in conjunction with creatine, increases this potential and gives the compound an additional properties. Creatine citrate, when used systematically, effects the energy storage, supporting the exercise capacity (strength and endurance) and increase of muscle mass. It has a regenerative ability through a pH, return to ATP balance in combination with anabolic activity of kinases activated by creatine. Due to the responsibility of the hormone insulin for the transport of creatine into the muscle cells, it is desirable to use creatine during meals or by the use of supplements (carbohydrate, carbohydrate-protein, insulin-like) and citrate creatine mono-preparation and multi-compaund supplements and as supplement to creatine stacks.
Dosage: Depending on the form of supplement, the type of exercise and weight, usually used one of the following creatine supplementation models:
1) supplementation cycle: 5-10g per day in 1-3 portions during the day, 2-5g per dose. Cycle length of about 4-12 weeks
2) constant supplementation: 0,03-0,05g per kg body weight for an extended period of time.
Caffeine (1,3,7-trimethylxanthine, 1-methylotheobromine) is a purine alkaloid occurring in the natural state in plants (Coffea arabica, Camelia sinensis, Paulinia cupana, Ilex paraguariensis), which acts as a natural pesticide, acting toxic to insects. Peculiar smell and taste also deters herbivores. Caffeine in the body inhibits the adenosine receptors in the brain, fighting fatigue and allowing for action activation. It has a beneficial effect on the metabolism of oxygen, which increases the exercise capacity (strength and endurance) and rapid post-workout recovery. In the sports supplementation, caffeine is used as a stimulant nervous system. It has the thermogenic potential and in combination with other substances (e.g. Polyphenols, both occurring in coffee beans, such as cocoa beans, tea leaves and mate) can effectively participate in the reduction of body fat. It is included in many dietary stimulants (creatine stacks, no-boosters, beverages). It is a component of fat burners. It is also in the form of mono-preparation supplements.
Dosage: 100-600 mg per day. Due to the long release of activity should not be used in the evening, before sleep.
ALA (alpha-lipoic acid) is a vitamin-like substance, a metabolite of catecholamines with strong antioxidant properties, it enhances anti-free-radicals action of some vitamins (A and E). ALA is synthesized at low levels by the body. It is a component of such products as broccoli, yeast, chicken liver, spinach. In the medicine it is used in the prevention of diabetic neuropathy (tissues shows a sensitivity to the insulin hormone, and it stimulates blood sugar levels). It has a positive effect on the functioning of the circulatory system and heart by the anti-arteriosclerosis action. It improves transport of creatine. It affects the storage of glycogen in muscle and liver.
Antioxidant properties of ALA are used in sports supplementation, along with the assimilation of nutrients. ALA is found in the form of mono-formula and is a compound of multicomponent products as: amino acids, creatine nitrogen boosters, as well as insulin-like (insulin-mimetic substances).
Leucine is an essential amino acid, one of the three branched chain amino acids, ketogenic, its isomer is isoleucine. It affects the secretion of anabolic hormones (insulin, combined carbohydrates), acts on enzymes (mTOR) starting the process of muscle protein synthesis and controlling its course. Protein synthesis by leucine is affecting the development of bones, muscles and skin. It reduces the fat tissue. Without the availability of leucine, protein synthesis is impossible. It naturally occurs in animal products (such as eggs, meat, dairy and fish), plant origin, and as a post-training supplements, BCAA, EAA, no-boosters, creatine stacks, carbohydrate supplements. Ir is also in the form of mono-preparation supplements. It is one of the most important amino acids for the athlete's body, basically in every sports discipline.
Dosage: The demand is 5-10 g / 24h, dosage pre- and post-workout and in the morning after waking up.
Isoleucine is an essential branched amino acid (BCAA), leucine-isomer. It has anti-catabolic action ( protects muscle against decay), glucogenic (an alternative energy source when the level of glucose after exercise decreases, helps for the regulation of blood glucose levels, reduces the deficiency of fatty acids), anti-catabolic (muscle protects against decay), reduces stress. It participates in the synthesis of proteins (including the synthesis of hemoglobin). It is an essential part of the regeneration of damaged tissues of the body, and after intense training. It occurs in products containing animal protein (meat and dairy products, eggs, dairy products) and plant (almonds, walnuts) and dietary supplements.
Isoleucine is applied with other branched chain amino acids: leucine, valine, and in the supplement complex type of BCAA, in the proportions: leucine: isoleucine: valine = 2: 1: 1. The supplements used in competitive sports requiring increased strength, the bigger share of isoleucine is used.
Dosage: No standard daily use. Frequently applied directly after the workout during the decrease of the glucose level of or at fatty acid deficiency.
Valine – is a branched essential amino acid, indispensible for the functioning of the nervous system (receiving of sensory information), involved in muscle protein synthesis and energy generation. Administration of additional doses of valine before exercise (or immediately after) has anti-catabolic effect, protecting the proteins and allowing them to rebuild. It is slightly stimulatory (delays symptoms of fatigue during workout), affecting the level and relations of neurotransmitters. It helps to protect the liver. It stimulates an increase in strength and muscle mass, participates in the reduction of body fat. BCAA, EAA, and other mixtures of amino acid supplementation, protein and protein supplements and carbohydrate-stacks, brings positive results in strength and endurance sports.
Valine deficiency can occur in case of increased energy needs of the body, as the result of stress and too much stress load.
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