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LittleMe Day: 3 capsules a day: 2 capsules in the morning and 1 in the afternoon, one hour after a meal (in case of nausea, it can be taken with or immediately after a meal).
LittleMe Night: 2 capsules in the evening, after a meal.
Folate supplementation during pregnancy constitutes prevention of neural tube defects in the fetus. However, unfavorable changes in the development of the nervous system related to the deficiency of this valuable nutrient occur already in the first weeks of pregnancy, when the woman often does not realize that fertilization has taken place. Therefore, it is recommended to start using folates already while trying for a baby.
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Magnesium (element from the group of alkaline earth metals, atomic no. 12, a chemical symbol - Mg), one of the most important health microelements, participates in the synthesis process of the disintegration of high energy compounds and processes of transformation of hydrocarbons and fats. It affects the dilation of blood vessels and lower blood pressure, prevents hypercoagulable state. Shortages affect cardiac arrhythmias, malignant muscle cramps, insomnia and anxiety. It is a component of many dietary supplements and found in foods such as whole grain bread, legumes, buckwheat, rice, fish, meat, as well as chocolate, cocoa and nuts.
Dosage of 100 - 500 mg / day
Citric acid (citric acid, E330) is a ingredient of almost every plant and animal cells, widely used in the food industry as an acidity regulator, emulsifier and stabilizer in order to prevent oxidation and preventing discolouration of the product. In the life processes it takes an active part in the Krebs cycle, a negative phosphofructokinase catalyst, enzyme accelerating the rate of glycolysis. In the sports supplementation used in conjunction with creatine. Preparations available at www.muscle-zone.pl
The iron part of the dye in the form of the heme (hemoglobin and myoglobin in meat), a non-haem (in plant), and enzymes responsible for transport and storage of oxygen in the body. It occurs in enzymes responsible for: the metabolism of fatty acids, prostaglandin biosynthesis, catabolism of tryptophan. The absorption of iron in plant is lower than in animal products. In plant foods, it is reduced by contained chemicals: phytates and oxalates, also calcium and high acidity (pH factor). Only 8% of the intake of iron is absorbed by the body and transported to the blood. For tts absorption is needed sufficient amount of: cobalt, manganese, copper and vitamin C. Iron itself is essential for the metabolism of B vitamins. Source of acquisition of iron are animal products (meat, organ meats, egg yolks) and plant products (whole grain bread, beans , cocoa, parsley, nuts, soy). Iron is also present in synthetic form as a component of vitamin-mineral and mineral and mono-preparation supplements, often enriched with vitamin C. Supplements containing iron compounds are recommended for athletes during intense training and those on a meatless diet (vegetarians and vegans).
Iron deficiency causes anaemia. Using a large amount of strong coffee or tea hinders the absorption of iron. Symptoms of iron deficiency are: insomnia, diarrhea, impaired body temperature, loss of papillae on the tongue, reduced exercise capacity, and reduced intellectual and psychological efficiency.
Excess iron reduces the absorption of other elements (e.g. zinc, copper), reduced immunity, causing tissue damage of some organs (kidney, liver, heart), increased risk of cancer.
Dosage: 3-12 mg per day.
Vitamin C (ascorbic acid) it is a vitamin soluble in body fluids, can be taken from foods (fruits and vegetables), or as drug derived synthetically. The largest of its resources can be found in broccoli, Brussels sprout, kale, black currant fruit and hawthorn, citrus fruits, tomatoes, Savoy cabbage, potatoes. In fact, intake of vitamin C of the food products does not limit the absorbed quantity. Vitamin C (ascorbic acid) is a potent antioxidant, it is an antitoxic, increasing the immune system due to the elimination of risk of bacterial contamination. Vitamin C prevents rupture of blood vessels, affects the blood cholesterol level. It substantially increases the absorption of iron. Inhibits the growth of cancer cells. Lowers stress levels.
Vitamin C deficiency causes abnormal development of connective tissue, cracking capillaries, abnormal calcification of bone tissue, impaired absorption of iron, scorbutus. With the lack of vitamin C, all kinds of injuries do not heal up properly. Vitamin C deficiency can be caused by smoking; each cigarette is destroying up to 100 mg of vitamin C.
Dosage: The demand is 60-80 mg daily. It does not limit the ability to consume higher doses. Some side effects may occur only with longer taking of synthetic vitamin C.
Ascorbic acid – vitamin C. Its biologically active form is the L-isomer, which negatively rotates the polarised light, so that it is a dextroisomer (laevorotatory vitamin C does not exist). It is a strong antioxidant; it reduces the amounts of free radicals, which reduces oxidative stress, a factor leading to cell apoptosis, which is why it is indicated to be a cause for premature ageing.
It supports the immune system functions and increases body system immunity. It is an essential element of the collagen synthesis path, which is why it positively affects the condition of connective tissue. Hence, it promotes also wound healing and increases the durability of capillary vessel. It is involved in transformations of tyrosine and carnitine as well as of some nutrients, so that it affects metabolism. It can also have an impact on the nervous system functions, as it reduces mental fatigue.
Higher supply of vitamin C is especially recommended in the periods of more intensive body system burden, after infections and in order to accelerate regeneration. The indications for increased supply of the vitamin are also hard physical work or intensive trainings.
Coenzyme Q10 (ubiquinone) is a physiological antioxidant, a fat soluble. It takes an active part in the process of creating the energy of ATP. intracorporeal synthesis requires the presence of B vitamins and trace elements, its intensification is caused by heavy training stress or under the influence of stress. Beneficial effects of Coenzyme Q10 has been found on the cardiovascular system, lipid profile (lowering LDL) cholesterol and reduce the risk of heart disease. Reducing the level of coenzyme Q10 starts when the age of 35, hence must be supplemented by preparations available in cosmetics (external action on the skin), and supplements intensifying the production of energy (for athletes strength) as well as mono-preparation supplement available at www.muscle-zone.pl.
Dosage: 10 - 90 mg / 24h
Selenium (element, chemical symbol Se, atomic no. 34, from chalcogenide, it is present in several allotropic forms). It is supplied the body with food in the form of seleno-amino acids (selenomethionine - gathering supplies, and selenocysteine – a component of glutathione peroxidase, deiodinase and seleno-proteins). Regulates the functioning of the thyroid gland. It affects the growth and development, including sexual development (by increasing production and sperm motility). It affects the flexibility of the tissue, removes some of the toxins from the body and destroys cancer cells and reduces the severity of menopause in women. Natural products containing selenium are seafood (sea fish, oysters, bladderwrack) and vegetable products (broccoli, onions, wheat germ, bran, tomatoes) and animal products (poultry, eggs). It is also included in the composition of vitamin-mineral and mineral supplements. Selenium supplementation is recommended as a dietary supplement of active people having diet poor in this element, and as a factor increasing the body's immunity.
Selenium deficiency increases the risk of developing cancer and heart disease. Symptoms of selenium deficiency are: cardiomyopathy, growth stoppage, disorders of detoxification processes which may lead to damage to the kidneys and liver.
An excess of selenium can lead to selenosis (the disease, the symptoms are: loss of hair, nail cracks, lesions).
daily demand of selenium for pregnant women 65 mcg; nursing mothers 75 mcg; men 7 mcg.
L-selenomethionine is a selenoamino acid and organic form of selenium. It is a combination of selenium with methionine (about 40% of selenium and 60% of the amino acid methionine per molecule) in which a sulphur molecule is replaced by selenium.
This form is absorbed very effectively via the digestive tract. It is believed that the bioavailability of selenium from L-selenomethionine is even 1.5-2 times greater than its non-organic forms. It is estimated that its bioavailability may exceed 90%. Furthermore, the half-life of L-selenomethionine is much longer than in non-organic forms – it is 252 days. This means that the absorbed selenium is accumulated for a long time in the body.
Selenium is a component of many key biochemical pathways. It helps protect the body from oxidative stress, prevents atherosclerosis, supports the immune system and brain function and optimises thyroid function. It has been demonstrated that selenium as L-selenomethionine may, among others, reduce the secretion of proinflammatory cytokines in female patients with Hashimoto’s thyroiditis..
As a dietary supplement, L-selenomethione is most often used to support thyroid, cardiac and immune function and stabilise cholesterol levels.
What is methylcobalamin?
Methylcobalamin is a biologically active form of vitamin B12. It is one of the two forms of this vitamin that may be used as cofactors in various reactions. It differs from popular cyanocobalamin in the presence of methyl group instead of cyanide, thanks to which it releases the organism from the need of neutralizing this harmful factor.
The methyl group from methylcobalamin may be transferred to homocysteine, thanks to which it comes back in the form of methionine in order to be further converted to SAMe, which is the main donor of methyl groups in our organism. These methyl groups may be then used in the processes of creatine production, in neurotransmitter metabolism and as DNA methylation, thanks to which we achieve proper energy level, better well-being and generally better condition of the organism. B12 is a coenzyme for three enzymes: isomerase, methyltransferase and dehalogenase.
Apart from the influence on the nervous system, the supply of vitamin B12 is also very important for the proper synthesis of red cells as well as hemoglobin and anemia prevention.
Methylcobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Calcium carbonate – a salt of carbonic acid and calcium, used in dietary supplements as one of the calcium forms, because of its high bioavailability. It is an alkaline salt, which is why it is used for neutralisation of the environment in the stomach.
Calcium is a macroelement necessary for the proper functioning of the body system. It is a building material of teeth and bones as well as it determines their mechanical strength. The proper supply of calcium prevents osteoporosis in elderly people and allows for the proper development of skeletal system in children. It is an activator of many enzymes, is involved in the inflammatory processes and regulates secretion of particular hormones. It is also essential for muscle contraction and determines blood coagulation. Moreover, calcium ions allow for transmission of nerve impulses by synapses, so that they regulate the proper neural transmission.
The demand for calcium increases with training intensity, which is why it is recommended for athletes to increase calcium supply. Calcium deficiency can be caused by high-protein diet.
Choline belongs to the soluble in liquids group of B vitamins. It is an organic nitrogen base containing lecithin, and acetylcholine. Together with inositol is involved in the metabolism of fats and cholesterol metabolism, preventing its accumulation on the walls of arteries and deposits in the gallbladder. With the penetration of the brain, contained lecithin improves its action and improves memory. Used in the treatment of age-related diseases (Alzheimer's). It occurs in plant foods: yeast, wheat germ, lecithin, green leafy vegetables and egg yolks.
Choline bitartrate a combination of one molecule of tartaric acid and choline, and in this embodiment is a precursor of acetylcholine (neurotransmitter). The human body is able to intracellular synthesis of choline, using the amino acid and vitamin B12. Because of the possibility of shortages of the above mentioned substances, it is necessary to supplement them with supplementation. Choline is a component of lecithin, which is the building substance of cells conditioning the proper functioning of the nervous system, and sphingomyelin, acting as an insulator of nerve tissue. Bitartrate affects the course of fat metabolism. In the sports supplementation of choline, bitartrate is used in the stimulating supplements,, affecting concentration and programs of weight control (fat reduction).
Dosage: 1-3 grams per day.
Inositol is an organic compound from the group of B vitamins soluble in fluids, present in the natural or synthetic form, synthesized in plants, such as brewer's yeast, beans, grapefruit, cabbage, sprout of wheat, melons and animal (liver). Along with choline is included in the lecithin. It affects the cell nutrition of the central nervous system (brain) by reducing the level of LDL (bad cholesterol), this makes it applicable in treatment of Alzheimer's disease and atherosclerosis. It has a calming effect. There has been a beneficial effect of inositol on the skin and hair reported.
Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
What is pyridoxine hydrochloride?
Pyridoxine hydrochloride is a basic, the most commonly used form of vitamin B6 in supplements and fortified foods. It is a vitamin soluble in water. It converts to the active form of the vitamin - pyridoxal phosphate.
Vitamin B6 is a cofactor in many enzymatic reactions. It takes part in the production of many neurotransmitters, such as GABA, serotonin and catecholamines and it takes part in the metabolism of amino acids, carbohydrates and lipids. It is an important factor for the process of the creation of red cells and hemoglobin and its deficit may be one of the factors causing anemia. This vitamin contributes to maintaining proper energy metabolism and is important for maintaining well-being and good psychological condition. Its presence supports the breakdown of pro-inflammatory homocysteine to cysteine and further metabolites, thanks to which it may decrease the risk of atherosclerosis and cardiological incidents.
Pyridoxine hydrochloride may be found in many vitamin B complexes and vitamin-mineral preparations available in the offer of muscle-zone.pl.
Iodine - more than two-thirds of iodine is stored in the thyroid gland and it is a component produced by it hormones - thyroxine and triiodothyronine, which are essential in the metabolism of proteins, carbohydrates and minerals and regulating the processes of growth, causing it usefulness in sports supplementation. It is also the ingredient of weight loss products. Regulates and controls body temperature. Natural source of acquisition of iodine are: bladderwrack, seafood, sea fish and onion and vegetables growing in soil containing this element and most of all iodized salt ..
Deficiency of iodine in the body cause hypothyroidism, and consequently overweight, mental slowing (cretinism inclusive). It is the cause of a goitre. Iodine deficiency can be caused by rhodanates and polyphenols (e.g. contained in cabbage and cauliflower), hemagglutinin found in legumes.
Excess iodine can result in inhibition of thyroid hormone synthesis (this happens in a small percentage of cases).
Dosage: Treatment of iodine should be done under medical supervision. Daily demand for adults is 150 mcg. For pregnant women daily demand increases to 175 mcg.
Potassium and sodium regulate the body's water resources, ensuring normal heart rhythm. Maintaining the proper level of potassium provides the proper oxidation of the brain, lowers blood pressure, increases the permeability of cell membranes (as an antagonist of calcium). It is a base-forming element. It is widely used in sports diet before and after training in the form of supplements, nutrients, vitamin-mineral preparations and minerals, concentrates and ready, isotonic and hypertonic beverages. Natural sources of acquisition of potassium are: vegetable products (bananas, citrus fruits, melons, mint leaves, green vegetables, potatoes) and animal products (sea fish, meat). Potassium is present in the form of organic compounds: citric acids, and fumarates gluconates and inorganic (chlorides, sulfates, oxides and carbonates).
Potassium deficiency (hypokalemia): excessive tiredness, headaches and irritability, problems with sleeping, muscle cramps, constipation. Potassium levels may drop sharply in the event of a reduction in blood sugar levels, prolonged starvation, severe diarrhea. They can occur when too much of strong coffee is consumed, with alcohol abuse and when eating too much sweets.
The excess of potassium (hyperkalemia) is often the cause of depression, hypotension, tingling in the extremities.
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