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Niacin can be applied both with a meal or on empty stomach. In case of any discomforts or gastrointestinal disorders, it is recommended to eat a meal to reduce these symptoms.
The proper dose of niacin should be fixed according to age, sex, physiological condition and related disorders. It is estimated that the optimal daily dose of niacin amounts for about 500 mg (1 tablet). This dose can be effective as a part of prevention of diet-related and cardiovascular diseases; however for therapeutic purposes it can be too small. It is believed that e.g. in case of regulation of lipid profile, the effective dose can be bigger, about 750–1,000 mg of niacin daily.
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