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Methylation processes are constantly occurring at many levels of the human body and are involved in a huge number of biochemical transformations that influence health. They determine the formation of compounds such as creatine, carnitine, coenzyme Q10, melatonin, choline, glutathione (a powerful antioxidant) or neurotransmitters responsible for the proper functioning of the brain. Methylation processes are also crucial for the proper course of the Krebs cycle, in which energy is generated in the form of ATP, as well as for amino acid metabolism and detoxification reactions in the liver. In addition, methylation is responsible for regulating the expression of some defective genes and thus protects the body against, e.g., the development of cancer.

A side product of the methylation reaction is homocysteine ​​– a sulfuric amino acid that is formed from methionine. It is an important compound for the functioning of the nervous system and is a donor of methyl groups. However, too high concentration of homocysteine adversely affects the body, induces inflammation and contributes to the formation of many diseases, especially those related to the cardiovascular system. Methylation disorders may lead to a decrease in homocysteine ​​neutralization efficiency, which may quickly lead to hyperhomocysteinemia and the afore-mentioned diseases. Besides, methylation disorders may result in the formation of cancer cells, increase oxidative stress; they also disrupt the metabolism of amino acids and slow down energy production.

Methylation disorders are very often caused by deficiencies of vitamins and compounds found naturally in the body. These include, e.g., vitamin B12, B6, folic acid, choline or S-adenosylmethionine. In order to increase the efficiency of methylation processes, it is worth to replenish these deficiencies. This is to be achieved by using proven dietary supplements that are available in our store. In addition, we offer special multicomponent formulas that support methylation and regulate homocysteine levels.

 

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Now Foods
18.37 $

Betaine improves the amplification of DNA by reducing the formation of secondary structure in GC-rich regions.

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Seeking Health
15.71 $

Contains L-5-MTHF and folinic acid. It supports cognitive functions and regulates homocysteine level.

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Seeking Health
23.70 $

Dietary supplement with high doses of active forms of vitamin B12 and B9.

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Jarrow Formulas
10.39 $

TMG Crystals™ provides trimethylglycine, an important methyl donor.

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Aliness
10.63 $

Diet supplement covering 11 key group B vitamins. It has a beneficial influence on the condition of the skin.

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Doctor's Best
14.11 $

The mostly bioactive form of folic acid in form of glucosamine salt of 5-MTHF acid.

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Source Naturals
23.70 $

TMG helps reduce homocysteine and protects the liver.

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Jarrow Formulas
11.18 $
(1)

Methyl B12 (methylcobalamin) is the most effective, the most readily absorbed form of vitamin B12.

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Life Extension
13.05 $

Methylcobalamin is the form of vitamin B12 active in the central nervous system.

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Aliness
7.43 $

Vitamin B6 in the active coenzyme form - P-5-P.

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Swanson
5.86 $

Encapsulated folate of the 4th generation – Quatrefolic®. Reduces the risk of hyperhomocysteinemia.

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Life Extension
21.04 $

5-MTHF is up to seven times more bioavailable than ordinary folic acid.

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Jarrow Formulas
7.19 $

The best available, methylated form of vitamin B12 in form of convenient chewable pastilles.

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Life Extension
14.65 $

Dietary supplement lowering the level of homocysteine in the organism.

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Jarrow Formulas
21.04 $

The complex of bioactive, enzymatic vitamins B6, B9 and B12. Methylcobalamin, methylfolate and pyridoxal 5'-phosphate.

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Source Naturals
from 11.98 $

Dimethylglycine source. It promotes energy processes that support mental and physical performance.

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Quicksilver
52.99 $

Vitamin B12 in the active methylated form. Supports proper functions of the nervous system.

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Source Naturals
14.65 $

Methylcobalamin is an active coenzyme form of vitamin B-12 and is essential for cell growth and replication.

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Life Extension
29.03 $

Methylcobalamin is the form of vitamin B12 active in the central nervous system.

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Aliness
9.29 $

A preparation containing the patented, active fourth generation folate, Quatrefolic®.

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Jarrow Formulas
23.70 $

Highly bioavailable, active 4th generation folate Quatrefolic®.

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Seeking Health
29.03 $
(1)

Product regulating homocysteine level in blood. Formula enriched in TMG additive.

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Seeking Health
13.05 $

Formula containing active forms of vitamin B12, high dose in one capsule. Appropriate for vegetarians.

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Seeking Health
26.36 $

Blend of homocysteine modulators. Supports normal methylation processes.

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Methyl B-12 Out of stock
Jarrow Formulas
19.97 $

Methyl B12 (methylcobalamin) is the most effective, the most readily absorbed form of vitamin B12.

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Douglas
23.70 $

The supplement containing Metafolin®. It supports proper development of the fetus and prevention of complic

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Homocystrol + TMG Out of stock
Douglas
39.68 $

Unique formula which supports fully healthy homocysteine metabolism.

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TMG Liquid Out of stock
Kirkman
39.68 $

Betaine anhydrous in the form of liquid with raspberry aroma. Doesn't contain gluten, casein or artificial colorings.

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