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B-group vitamins are compounds soluble in water, therefore they are not stored in the organism and their excess is excreted.
In order to avoid and minimize the risk of the phenomenon called niacin flush, take the preparation with a meal.
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Vitamin B3 (vitamin PP, niacin, nicotinic acid, nicotinamide) is niacinamide niacin. It is used in interaction with vitamins B1, B2 and B6 in the synthesis of hormones during lactation. It provides proper functioning of the brain and nervous system. It is helpful in inflammatory conditions of the skin. Required for synthesis of sex hormone, estrogen, testosterone, cortisone, and insulin. It does not lose its properties in the manufacturing and storage. The source of acquiring vitamins PP are both products of animal origin (the lean meat, eggs, fish) and vegetable origin (dates, figs, hazelnuts, plums).
Dosage: 2-12 mg / day for children, 14 mg / day for women, 16 mg / day for men and 17-18 mg / day for pregnant or nursing women.
Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
Metafolin® is a stable and bioactive form of folic acid with high bioavailability, patented by the German pharmaceutical company Merck KGaA. After ingestion, the compound may be directly utilised by the body, irrespective of the presence of disorders (e.g. a MTHFR gene mutation) which hinder conversion of other forms of folic acid into their active forms.
The efficacy of Metafolin® has been confirmed by numerous clinical studies. For instance, it has been demonstrated that this is the only form of folic acid which is capable of crossing the blood-brain barrier. What is more, Metafolin®has passed extensive toxicological safety testing.
In supplementation, Metafolin® is used primarily in women planning pregnancy or who are pregnant and individuals with methylation disorders and elevated homocysteine levels. Scientists also suggest that there is a correlation between folic acid deficiency in the cerebrospinal fluid and the risk of dementia and depression. Because of that, it may be effective in the prevention of neurodegenerative diseases and depression.
Metafolin® can be used not only in dietary supplements but also as an addition to drinks and food.
Dosage: according to individual requirements for folic acid.
Biotin (vitamin H, co-enzyme R) is in a group of B vitamins, due to the presence of sulphur compounds it is involved in the synthesis of ascorbic acid (vitamin C). Also synthesized in the intestines. It enhances the production of hormones and regulates cholesterol levels. It reduces muscle pain. It prevents hair loss and graying of hair. It soothes the skin inflammations. No toxic effects. Often combined with other B group vitamins and vitamin A. The natural sources of biotin are: whole grain bread, yeast, eggs (yolk), milk, brown rice and cheese.
Daily demand: 100-300 mg per day
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Intrinsic factor (IF) is a kind of glycoprotein produced by the parietal cells of the stomach. It has a key role in the absorption of vitamin B12. After binding to intrinsic factor, the vitamin forms a special complex which can be absorbed in the small intensine.
Impaired production of intrinsic factor may be genetically determined, but it occurs equally often due to damage to the gastric mucosa caused by Helicobacter pylori infection. IF synthesis is also seriously inhibited by gastric parietal cell antibodies. IF deficiency limits the absorption of vitamin B12 and may consequently lead to major deficiencies and subsequent diseases.
Purified intrinsic factor, obtained from porcine gastric mucosa, is the most frequent form used in supplementation. It is added to preparations with vitamin B12 or B vitamin complexes to improve cobalamin absorption.
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