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|Servings: 180 caps.|
The preparation contains ideal proportions and doses of vitamins and minerals essential for the health of joints. The suggested dose is 2 capsules a day. It is worth dividing it into two portions and take at a few hour intervals. Due to the fact that vitamin D3 contained in the preparation is soluble in fats, it should be taken during a meal containing a source of fat.
The absorption of active ingredients may be inhibited by coffee, tea and large amounts of fiber. Because of this, the space of a few hours should be preserved between drinking/eating these products and supplementation.
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Vitamin D belongs to fat soluble vitamins, occurs in three forms: calciferol (vitamin D1) ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3), it is formed under the action of sunlight for at least 15 minutes per day. In the absence of sunlight it should be administered in the diet in the form of fish oil (Vitamin A + D3) and fish oils. It is responsible for the absorption of calcium and phosphorus. It is the building substance of bone tissue particularly necessary during pregnancy, childhood, and for athletes. It is a component of dietary supplements and nutrients among competetive athletes. Deficiency of vitamin D causes children growth inhibition, and rickets.
For adults - deficiency causes osteomalacia.
Excess of vitamin D causes headaches, alopecia, nausea, drowsiness, blurred vision, pain in the long bones, the deposition of calcium deposits.
Dosage: 400 IU units during the day.
Cholecalciferol, or vitamin D3, is an organic chemical that belongs to the family of D vitamins. It is naturally found in fatty fish, fish oil, egg yolks, milk and dairy products. It is also synthesized in the human body. It is formed from 7-dehydrocholesterol present in the keratinocytes of the spinous and the basal layers of the epidermis, and a pre-requisite for initiating this process is the action of 290-315 nm wavelength UVB radiation on the skin.
Cholecalciferol is a biologically inactive compound. In the body, it undergoes enzymatic hydroxylation – first in the liver, with the participation of 25-hydroxylase, when calcidiol is formed and secondly in the kidneys, where under the influence of 1-α-hydroxylase, calcidiol is converted into the final active form – calcitriol.
The most important role of vitamin D3 in the body is the regulation of calcium-phosphate metabolism, which directly affects normal skeletal mineralization. In addition, it is involved in cell proliferation and differentiation, insulin secretion, as well as in some functions of the nervous, endocrine and immune systems.
Cholecalciferol is the most popular form of vitamin D used in dietary supplements. Studies show that supplementation with vitamin D in this form most effectively and rapidly raises the level of 25 (OH) D3 – a metabolite that is a marker of the level of vitamin D in the body.
Dosage: according to RDI standards for individual age groups.
What is Vitamin K2?
Vitamin K2 belongs to fat-soluble vitamins It is an important activator of many enzymes and proteins It shows a positive action on calcium balance by activating MGP protein and osteocalcin. This results in the removal of calcium deposits from blood vessel walls and transport of ions of this element to the area where it fulfills its function – teeth and bones. It reduces therefore the calcification of blood vessels and thus the risk of cardiovascular diseases. Moreover, it is a constituent of coagulation factors and cosequently prevents haemorrhages. It shows a synergistic action in combination with vitamin D and magnesium.
Vitamin K2 in the form of a dietary supplement of renowned brands e.g. Now Foods, Swanson, Life Extension, Jarrow Formulas and Thorne Research) can be found in formulas available at www.muscle-zone.pl
What is menaquinone?
Menaquinone is the term used for vitamin K2. It appears in short- and long-chain forms, the most popular of which are MK-4 and MK-7, containing respectively 4 and 7 isoprene residues in the side chains.
Vitamin K2 exhibits the widest spectrum of its activity by means of osteocalcin, which it has the ability to activate. By means of this hormone produced by bone cells, it may support the state of mineral density of bones and the condition of blood vessels and lower the risk of circulatory diseases. An interesting property of this vitamin is stimulation of Leydig cells to synthesize testosterone, which will be of interest especially to men. K2 also has neuroprotective properties, protecting from excitotoxicity caused by glutamate and oxidative stress from glutathione deficiency. Osteocalcin may also increase adiponectin release from fatty cells, thanks to which it is possible to achieve better insulin sensitivity and decrease inflammations.
Menaquinone is contained in dietary supplements available in the offer of muscle-zone.pl.
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Magnesium (element from the group of alkaline earth metals, atomic no. 12, a chemical symbol - Mg), one of the most important health microelements, participates in the synthesis process of the disintegration of high energy compounds and processes of transformation of hydrocarbons and fats. It affects the dilation of blood vessels and lower blood pressure, prevents hypercoagulable state. Shortages affect cardiac arrhythmias, malignant muscle cramps, insomnia and anxiety. It is a component of many dietary supplements and found in foods such as whole grain bread, legumes, buckwheat, rice, fish, meat, as well as chocolate, cocoa and nuts.
Dosage of 100 - 500 mg / day
Magnesium oxide – the most common form of this macroelement in supplementation that is essential to the human body. It belongs to a group of key intracellular cations and that is why its adequate levels are critical to maintaining the body’s homeostasis. An active lifestyle increases requirements for magnesium and that is why its supplementation is recommended strongly to athletes.
The most common symptoms associated with magnesium deficiencies are muscle cramps and eye twitches. This is connected with a significant impact of magnesium ions on the efficiency of the nervous system. Its adequate intake helps maintain neuromotor fitness. Deficiencies of this element are also said to aggravate symptoms of depression.
What is more, magnesium supplementation supports healthy cardiovascular function. It is suggested that its deficiencies promote the development of atherosclerotic lesions and hypertension. Too low dietary magnesium intake is associated with arrythmia and increased risk of heart attack.
Magnesium supplements are recommended to individuals doing hard mental work and learning. Its healthy levels enhance focus and may facilitate learning. It has a beneficial impact on sleep quality.