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Supplement is dedicated for everyone who needs daily stimulation of central nervous functions and mild stimulation during periods of intense effort and increased fatigue. Pro-cognitive activity may be particularly useful among people performing difficult intellectual work, or students studying for important exams.
The formulation should not be used by persons under 18 years of age, pregnant or nursing women. Individuals taking centrally acting drugs (especially from the group of MAO inhibitors), as well as those suffering from various types of ailments should consult a physician. During supplementation, one should not consume alcohol and other stimulants.
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Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
Pyridoxal 5-phosphate (P-5-P) - the form of vitamin B6, called coenzymatic, considered the best assimilable form of this vitamin by the human organism. This is related to direct metabolic activity of pyridoxal-5-phosphate in the human organism. It does not have to be subjected to biochemical transformations in the organism in order to be able to enter metabolic pathways as a biologically active ingredient.
Vitamin B6 is an incredibly important factor regulating the work of many processes in the organism due to its role in the organism as a coenzyme, essential for the activation of many important enzymes. Thanks to this, it regulates metabolism at many levels and its proper supply is conducive to maintaining homeostasis of the organism.
Another aspect of effectiveness of vitamin B6 is its influence on the normalization of emotional states. It is conducive to relaxation, facilitates falling asleep and falling in a deep, the most valuable sleep. Special influence on P5P on the psyche is proven in women before menstruation, as it demonstrates considerable ability to reduce the symptoms of the pre-menstrual syndrome.
Supplementation with vitamin B6 also demonstrates positive influence on the functions of the nervous system. It is conducive to the nourishment of neuronal tissues and optimizes the secretion of neurotransmitters, thanks to which it promotes nervous transmission and demonstrates neuroprotective properties. It was proven that vitamin B6 may decrease the risk of developing Parkinson’s disease.
Some sources also suggest the ability of pyridoxal 5-phosphate to reduce the risk of cancer. This effectiveness is noted especially in relation to breast cancer.
Vitamin B12 (cobalamin, cyanocobalamin) is a vitamin soluble in liquids. Participates in the production of red blood cells and is essential in the absorption of iron by the body. It calming effect, a positive effect on concentration and memory. Intensifies its action in cooperation with folic acid (vitamin M). Usually occurs in animal products, fish and dairy products. It contains trace elements.
Vitamin B12 deficiency can lead to pernicious anaemia, general and immunity weakness, inhibiting of growth and damage to the myelin sheath of nerves.
What is methylcobalamin?
Methylcobalamin is a biologically active form of vitamin B12. It is one of the two forms of this vitamin that may be used as cofactors in various reactions. It differs from popular cyanocobalamin in the presence of methyl group instead of cyanide, thanks to which it releases the organism from the need of neutralizing this harmful factor.
The methyl group from methylcobalamin may be transferred to homocysteine, thanks to which it comes back in the form of methionine in order to be further converted to SAMe, which is the main donor of methyl groups in our organism. These methyl groups may be then used in the processes of creatine production, in neurotransmitter metabolism and as DNA methylation, thanks to which we achieve proper energy level, better well-being and generally better condition of the organism. B12 is a coenzyme for three enzymes: isomerase, methyltransferase and dehalogenase.
Apart from the influence on the nervous system, the supply of vitamin B12 is also very important for the proper synthesis of red cells as well as hemoglobin and anemia prevention.
Methylcobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
Tyrosine - endogenous amino acid (synthesized within the body), one of the 22 protein amino acids building. It occurs naturally in animal food products (eggs, dairy, meat). If the deficiency, it can be synthesized by hydroxylation of phenylalanine, capable of being converted to tyrosine in the liver. It is a precursor of neurotransmitters: dopamine (the group of catecholamines, participating in the processes occurring in the nervous system, causing muscle coordination and participates in the synthesis of many hormones) and noradrenaline (counteracting stress, stimulating the heart and circulatory system, and increasing glycogenolysis and lipolysis participating in the processes of energy transformations). Tyrosine is a precursor of thyroid hormones responsible for the rate of change in metabolic processes and pigment (melanin). In the supplementation, preparations containing tyrosine are used in programs reducing body fat (weight loss), improve mood and are stimulants.
Dosage: Customarily 500-2000 mg per day.
Alpha GPC (L-Alpha Glucerylphosphorylcholine, alphaglycerylphosphorylcholine) occurs naturally in the brain and milk. It is a chemical compound (a derivative of choline and its provider in the body) providing a precursor for the synthesis of acetylcholine, which is a neurotransmitter. Probably it has an impact on the secretion of the growth hormone that allows the intensification of tissue regeneration and it is improving the general condition and forming of proper body building.
The medicine uses it in the neurological treatments (stress, depression). In the sports supplementation is rarely used. It is a part of the supplements supporting a night renewal process.
Caffeine (1,3,7-trimethylxanthine, 1-methylotheobromine) is a purine alkaloid occurring in the natural state in plants (Coffea arabica, Camelia sinensis, Paulinia cupana, Ilex paraguariensis), which acts as a natural pesticide, acting toxic to insects. Peculiar smell and taste also deters herbivores. Caffeine in the body inhibits the adenosine receptors in the brain, fighting fatigue and allowing for action activation. It has a beneficial effect on the metabolism of oxygen, which increases the exercise capacity (strength and endurance) and rapid post-workout recovery. In the sports supplementation, caffeine is used as a stimulant nervous system. It has the thermogenic potential and in combination with other substances (e.g. Polyphenols, both occurring in coffee beans, such as cocoa beans, tea leaves and mate) can effectively participate in the reduction of body fat. It is included in many dietary stimulants (creatine stacks, no-boosters, beverages). It is a component of fat burners. It is also in the form of mono-preparation supplements.
Dosage: 100-600 mg per day. Due to the long release of activity should not be used in the evening, before sleep.
L-DOPA - an amino acid, commonly called Levodopa, enantiomer of L-dihydroxyphenylalanine, belonging to the group of catecholamines. It is present in the human organism on the pathway of adrenaline biosynthesis. It is produced from tyrosine and is a precursor for subsequent reactions of compounds produced in this chain - dopamine, noradrenaline and adrenaline.
Thanks to the ability to cross blood-brain barrier, it is an incredibly effective supplement as for the promotion of cognitive functions and emotional states. It is conducive to the synthesis of dopamine and therefore it promotes its concentration and effectiveness in the organism. In this way, it positively influences the level of motivation and well-being. Due to the presence of dopamine in the extrapyramidal system, where it is responsible for neuromotor coordination, it is used in the therapy of Parkinson’s disease (the etiology of which consists in disturbing the synthesis of this neurotransmitter).
More globally, supplementation with levodopa may be conducive to the synthesis of subsequent catecholamines on the pathway of their biosynthesis, i.e. noradrenaline and final adrenaline. Therefore, it may demonstrate a stimulating effect.
Supplementation with L-DOPA also positively influences the secretion of testosterone and the human growth hormone. Due to its wide effectiveness in the organism, it may be also effectively used in order to promote sexual functions in men.
L-theanine is an amino acid, not building proteins, occurring naturally in the dried green tea leaves, absorbed from the gastrointestinal tract, overcomes easily blood-brain barrier, affecting the nervous system and the relation between neurotransmitters (e.g.dDopamine, serotonin, gamma-aminobutyric acid), with a relaxing effect and increases the psycho-physical capacity, (concentration, memory, alertness). Recommended for use for people burdened with considerable physical effort, athletes of sport disciplines that require concentration and memory, also for students in the period before exams. Available in the form of mono-preparations and multi-component relaxing and post-workout anti-stress supplements..
Dosage: customarily used in supplementation 50-200mg per day
Tyramine (4-hydroxyphenylethylamine) is a derivative of tyrosine, occurring in the natural plant food (such as wine, tea, chocolate) and animal origin food (red meat, full-fat cheese). It affects the intensity of burning depot fat (lipolysis). Excessive consumption of tyramine can cause side effects (increased blood pressure, headaches). Tyramine is a component of slimming supplements and stimulants (in combination with caffeine).
Bioperine - a black pepper extract, which is a source of plant alkaloid – piperine, enhancing secretion of digestive juices, affecting the increase of the availability of food (and other chemicals) and regulating the digestive tract. Through the access to food and chemicals, it indirectly influences the development of muscle tissue and increases the exercise capacity (psychophysical). There has been a positive effect on the immune system and the intensification of the lipolysis processes observed. Available in the form of mono-preparations and as a component of supplements and nutrients.
Dosage: 5-10 mg per day.
Huperzia serrata - a plant family Huperziaceae occurring in the Far and Middle East. It is a source of huperzine A - an alkaloid having the ability to penetrate the blood-brain barrier, which is a negative catalyst for the degradation of acetylcholine, that improves nerve conduction and having a significant impact on the concentration, cognition and memory. It helps to mitigate the effects of oxidative stress, and prevents the depressions, has neuroprotective actions improving well-being.. In the sports supplementation it is recommended at pre-workout, pre-effort and during workouts in order to improve concentration, as an component of advanced creatine stack, no-boosters as well as herbal remedies that improve mood.
Huperzine A - an alkaloid of plant origin having the ability to penetrate the blood-brain barrier, it is a negative catalyst for the degradation of acetylcholine, that improves nerve conduction and having a significant impact on the concentration, cognition and memory. It helps mitigate the effects of oxidative stress, and prevents the depressions, has neuroprotective actions improving well-being. In the sports supplementation it is recommended at pre-workout, pre-effort and during workouts in order to improve concentration, as an component of advanced creatine stack, no-boosters as well as herbal remedies that improve mood.
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