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It is assumed that 10 mg of manganese per day (1 capsule) is the upper, safe limit, and supplementation with such a dose should not give any undesirable effects. Sine the excess manganese is toxic, you should follow the manufacturer's instructions and do not use more than 1 capsule a day.
People with liver dysfunctions are particularly exposed to the accumulation of manganese in the body and its toxicity, therefore, before implementing the supplementation, they should consult a specialist.
Manganese, of which a natural source is chocolate, grain products with whole grain, nuts, legumes and dried cranberry, is a component of enzymes and their activator. It stimulates the properties and functionality of connective tissue and provides proper functioning of the brain. It affects the function of the pancreas, ensuring proper insulin metabolism and condition of the bone and joints. Magnesium deficiency contributes to serious disorders in synthesis of hyaluronic acid and chondroitin, reduction in insulin sensitivity of tissues, affects bone resorption. Manganese chelates are used in complexometry in chemical analysis and in medicine for the treatment of severe poisoning (antitoxin) by heavy metals, in sports supplementation, manganese impact on the functioning of the locomotor system is used. It is a component of the so-called regenerators of joints and a vitamin-mineralizing and mineralizing supplements.