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  • NOW FOODS Niacinamide 500mg 100 kaps.
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Niacinamide 500mg Niacinamide 500mg

Now Foods Niacinamide  is a supplement with a high dose of active form of vitamin B3 which helps fight pellagra (results of a deficiency of this vitamin) and brings all benefits of its supplementation.

Niacinamide , otherwise known as nicotinamide, is a fully active, water-soluble and amide form of vitamin B3. Unlike other active form of this vitamin – niacin, it does not have a “flush effect” on your skin. This effect results from the effect of niacin on the activation of GPR109A receptors in Langerhans cells in the skin which induces the synthesis of prostaglandins with a vasodilating action on local blood vessels. Consequently, increased flow to the skin causes reddening and unpleasant tingling sensation.

A precursor of energy carriers
After reaching the intestines, niacinamide is absorbed and transported into the liver and other tissues in the form of NAD and NADP coenzymes. These substances are vital to the human body because they are important elements in cellular respiration and thus responsible for energy production. In addition, they influence the repair of damaged DNA. Owing to that, they block mutations in the body, thereby inhibiting carcinogenesis.

For healthy skin
Nicotinamide has a very positive impact on the skin. It shows a photoprotective action by providing energy for keratinocytes which were weakened under the exposure to UV radiation. It has been demonstrated that sustained supplementation with this form of vitamin B3 inhibits the secretion of sebum, i.e. an oily excretion of the skin, whose excess amounts are responsible for the formation of acne and other skin conditions. It stimulates the formation of ceramides, namely lipids from the stratum corneum of the epidermis, maintaining their proper structure. Furthermore, it promotes keratin synthesis and keratinocyte differentiation.

Regulation of the lipid balance
A positive impact of niacinamide has been proven in reference to fat, carbohydrate and protein metabolism. Nicotinamide does not affect cholesterol levels itself but it is partly converted in the body to niacin which has the ability to decrease LDL cholesterol and triglyceride levels during the stimulation of HDL cholesterol synthesis. It has a beneficial effect because nowadays normal LDL-HDL ratio is disturbed, which is consequently followed by atherosclerotic plaque formation in the presence of triglycerides. This has a very negative impact on the cardiovascular function. By affecting lipids found in the blood, it contributes to the synthesis of many hormones whose basic constituents are lipid compounds. A decrease in triglyceride levels is triggered by noncompetitive inhibition of the enzyme which synthesise them – DGAT2. Because of that, it contributes also to inhibiting the release of LDL and VLDL cholesterol.

A healthy cardiovascular system
Apart from atherosclerotic plaque formation, another advantage of proper nicotinamide supplementation to the cardiovascular system is its vasodilating action. By inducing an increase of HDL cholesterol levels, it stimulates indirectly the formation of nitrogen oxide which has a vasodilating effect on smooth muscle tissue of blood vessels. In addition, the amide of vitamin B3 stimulates the formation of many prostaglandins which show such action as well. As a result, niacinamide and niacin lower blood pressure and aid in migraines caused by vascular lesions.

Anti-inflammatory properties
Vitamin B3 can inhibit an exaggerated immune response to different factors. It reduces the secretion of such cytokins as  IL-1β, IL-6, IL-8 and TNFα. Consequently, it inhibits their overactivity in response to inflammation. Moreover, it can be used as an agent delaying the development of type 1 diabetes. This is the result of the inhibition of immune responses which damages normal pancreatic β cells responsible for insulin production. By modulating cytokins and other crucial elements of the immune system, this niacinamide has the ability to inhibit leukocyte chemotaxis, release lysosomal enzymes and trigger mastocyte degranulation. It inhibits the growth of Propionibacterium acnes, thereby reducing the formation of acne vulgaris.

The supplement Niacinamide is recommended for everyone, especially active people because a small content of vitamin B3 in food, poor intestinal absorption and lifestyle can cause too low concentration of this vitamin in the body. It should interest particularly individuals with various skin problems and persons who want to maintain youthful appearance for a long time. What is more, it will help avoid negative effects of the vitamin deficiency. 

Out Of Stock
4 2
4

Amid niacyny działa także przeciwdepresyjnie, przeciwlękowo i można go stosować w przypadku chorób stawów.
4

Amid Niacyny działa także przeciwdepresyjnie, przeciwlękowo (prawdopodobnie przez obniżanie stanów zapalnych muzgu) oraz można go stosować w przypadku chorób stawów.
Niacinamide 500mg Niacinamide 500mg 100 caps.
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Niacinamide 500mg 100 caps.

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Notify me of availability

- Delivery even day after tomorrow

- Foreign shippment from 5.89 $ Every 86.23 $ reduces shipping costs by 2.87 $

You have got questions about the product

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01709231594 (mon.-fri 900-1700)

Description
  • Has a positive impact on fat metabolism
  • A precursor for the production of NAD and NADP
  • Does not cause a niacin like flush
  • Shows immunomodulatory properties
  • Prevents signs of skin ageing
  • Eases vascular headaches
  • Inhibits atherosclerotic plaque formation
  • Prevents cardiovascular diseases

Now Foods Niacinamide  is a supplement with a high dose of active form of vitamin B3 which helps fight pellagra (results of a deficiency of this vitamin) and brings all benefits of its supplementation.

Niacinamide , otherwise known as nicotinamide, is a fully active, water-soluble and amide form of vitamin B3. Unlike other active form of this vitamin – niacin, it does not have a “flush effect” on your skin. This effect results from the effect of niacin on the activation of GPR109A receptors in Langerhans cells in the skin which induces the synthesis of prostaglandins with a vasodilating action on local blood vessels. Consequently, increased flow to the skin causes reddening and unpleasant tingling sensation.

A precursor of energy carriers
After reaching the intestines, niacinamide is absorbed and transported into the liver and other tissues in the form of NAD and NADP coenzymes. These substances are vital to the human body because they are important elements in cellular respiration and thus responsible for energy production. In addition, they influence the repair of damaged DNA. Owing to that, they block mutations in the body, thereby inhibiting carcinogenesis.

For healthy skin
Nicotinamide has a very positive impact on the skin. It shows a photoprotective action by providing energy for keratinocytes which were weakened under the exposure to UV radiation. It has been demonstrated that sustained supplementation with this form of vitamin B3 inhibits the secretion of sebum, i.e. an oily excretion of the skin, whose excess amounts are responsible for the formation of acne and other skin conditions. It stimulates the formation of ceramides, namely lipids from the stratum corneum of the epidermis, maintaining their proper structure. Furthermore, it promotes keratin synthesis and keratinocyte differentiation.

Regulation of the lipid balance
A positive impact of niacinamide has been proven in reference to fat, carbohydrate and protein metabolism. Nicotinamide does not affect cholesterol levels itself but it is partly converted in the body to niacin which has the ability to decrease LDL cholesterol and triglyceride levels during the stimulation of HDL cholesterol synthesis. It has a beneficial effect because nowadays normal LDL-HDL ratio is disturbed, which is consequently followed by atherosclerotic plaque formation in the presence of triglycerides. This has a very negative impact on the cardiovascular function. By affecting lipids found in the blood, it contributes to the synthesis of many hormones whose basic constituents are lipid compounds. A decrease in triglyceride levels is triggered by noncompetitive inhibition of the enzyme which synthesise them – DGAT2. Because of that, it contributes also to inhibiting the release of LDL and VLDL cholesterol.

A healthy cardiovascular system
Apart from atherosclerotic plaque formation, another advantage of proper nicotinamide supplementation to the cardiovascular system is its vasodilating action. By inducing an increase of HDL cholesterol levels, it stimulates indirectly the formation of nitrogen oxide which has a vasodilating effect on smooth muscle tissue of blood vessels. In addition, the amide of vitamin B3 stimulates the formation of many prostaglandins which show such action as well. As a result, niacinamide and niacin lower blood pressure and aid in migraines caused by vascular lesions.

Anti-inflammatory properties
Vitamin B3 can inhibit an exaggerated immune response to different factors. It reduces the secretion of such cytokins as  IL-1β, IL-6, IL-8 and TNFα. Consequently, it inhibits their overactivity in response to inflammation. Moreover, it can be used as an agent delaying the development of type 1 diabetes. This is the result of the inhibition of immune responses which damages normal pancreatic β cells responsible for insulin production. By modulating cytokins and other crucial elements of the immune system, this niacinamide has the ability to inhibit leukocyte chemotaxis, release lysosomal enzymes and trigger mastocyte degranulation. It inhibits the growth of Propionibacterium acnes, thereby reducing the formation of acne vulgaris.

The supplement Niacinamide is recommended for everyone, especially active people because a small content of vitamin B3 in food, poor intestinal absorption and lifestyle can cause too low concentration of this vitamin in the body. It should interest particularly individuals with various skin problems and persons who want to maintain youthful appearance for a long time. What is more, it will help avoid negative effects of the vitamin deficiency. 

Directions for use
Manufacturer

Composition

Composition

Container size: 100 capsulesServing size: 1 capsuleServings per container: 100
per 1 capsuleamount%DV
Niacin (Vitamin B-3) (as niacinamide)500 mg2500%

Other ingrednients

Gelatin (capsule) and Magnesium Stearate (vegetable source).

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